Perturbed mitochondria-ER contacts in live neurons modelling Alzheimer's disease amyloid pathology.
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DOI: 10.1242/jcs.229906
Abstract: Reports using fixed fibroblasts from familial and sporadic Alzheimer's disease (AD) patients indicated upregulated mitochondria-endoplasmic reticulum contacts (MERC) as a hallmark of AD. Despite its potential significance, the relevance of these results is limited because… read more here.
Keywords: alzheimer disease; pathology; live neurons; merc ... See more keywords