Early administration of COVID‐19 convalescent plasma with high titer antibody content by live viral neutralization assay is associated with modest clinical efficacy
Sign Up to like & getrecommendations! Published in 2022 at "American Journal of Hematology"
DOI: 10.1002/ajh.26531
Abstract: The efficacy of COVID‐19 convalescent plasma (CCP) as a treatment for hospitalized patients with COVID‐19 remains somewhat controversial; however, many studies have not evaluated CCP documented to have high neutralizing antibody titer by a highly… read more here.
Keywords: neutralization assay; high titer; live viral; viral neutralization ... See more keywords
Monogenic susceptibility to live viral vaccines.
Sign Up to like & getrecommendations! Published in 2021 at "Current opinion in immunology"
DOI: 10.1016/j.coi.2021.05.006
Abstract: Live attenuated viral vaccines (LAV) have saved millions of lives globally through their capacity to elicit strong, cross-reactive and enduring adaptive immune responses. However, LAV can also act as a Trojan horse to reveal inborn… read more here.
Keywords: susceptibility live; immunity; viral vaccines; monogenic susceptibility ... See more keywords
Correlation of SARS-CoV-2 Viral Neutralizing Antibody Titers with Anti-Spike Antibodies and ACE-2 Inhibition among Vaccinated Individuals
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DOI: 10.1128/spectrum.01315-22
Abstract: Live viral neutralizing antibody titers are an accepted measure of immunity; however, testing procedures are labor-intensive. COVID-19 antibody and angiotensin converting enzyme-2 (ACE-2) levels have been used as surrogates to live viral neutralizing antibody titers;… read more here.
Keywords: live viral; antibody titers; correlation; neutralizing antibody ... See more keywords
Live Viral Vaccine Neurovirulence Screening: Current and Future Models
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DOI: 10.3390/vaccines9070710
Abstract: Live viral vaccines are one of the most successful methods for controlling viral infections but require strong evidence to indicate that they are properly attenuated. Screening for residual neurovirulence is an important aspect for live… read more here.
Keywords: neurovirulence screening; viral vaccine; screening current; neurovirulence ... See more keywords