APOE gene polymorphism in long-lived individuals from a central China population
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-03227-5
Abstract: Previous studies from European and East Asian cohorts reported conflicting results over whether and how the frequencies of the three common alleles, ε2, ε3 and ε4, of the apolioprotein E gene (APOE), in long-lived individuals… read more here.
Keywords: lived individuals; central china; individuals central; gene ... See more keywords
Plasma proteome profiling of healthy individuals across the life span in a Sicilian cohort with long‐lived individuals
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DOI: 10.1111/acel.13684
Abstract: The study of healthy human aging is important for shedding light on the molecular mechanisms behind aging to promote well‐being and to possibly predict and/or avoid the development of age‐related disorders such as atherosclerosis and… read more here.
Keywords: lived individuals; plasma proteome; long lived; age ... See more keywords
Long-Lived Individuals Show a Lower Burden of Variants Predisposing to Age-Related Diseases and a Higher Polygenic Longevity Score
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms231810949
Abstract: Longevity is a complex phenotype influenced by both environmental and genetic factors. The genetic contribution is estimated at about 25%. Despite extensive research efforts, only a few longevity genes have been validated across populations. Long-lived… read more here.
Keywords: lived individuals; longevity; age related; tomm40 apoe ... See more keywords