CD28 Regulates Metabolic Fitness for Long-Lived Plasma Cell Survival
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DOI: 10.1016/j.celrep.2020.107815
Abstract: SUMMARY Durable humoral immunity against epidemic infectious disease requires the survival of long-lived plasma cells (LLPCs). LLPC longevity is dependent on metabolic programs distinct from short-lived plasma cells (SLPCs); however, the mechanistic basis for this… read more here.
Keywords: cd28 regulates; cd28; survival; lived plasma ... See more keywords
Survival of Long-Lived Plasma Cells (LLPC): Piecing Together the Puzzle
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DOI: 10.3389/fimmu.2019.00965
Abstract: Durable humoral immunity is dependent upon the generation of antigen-specific antibody titers, produced by non-proliferating bone marrow resident long-lived plasma cells (LLPC). Longevity is the hallmark of LLPC, but why and how they survive and… read more here.
Keywords: plasma cells; cells llpc; survival; lived plasma ... See more keywords
Potential of Polyethyleneimine as an Adjuvant To Prepare Long-Term and Potent Antifungal Nanovaccine
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.843684
Abstract: Background Candida albicans infections are particularly prevalent in immunocompromised patients. Even with appropriate treatment with current antifungal drugs, the mortality rate of invasive candidiasis remains high. Many positive results have been achieved in the current… read more here.
Keywords: long term; long lived; lived plasma; plasma cells ... See more keywords
B Cell Kinetics upon Therapy Commencement for Active Extrarenal Systemic Lupus Erythematosus in Relation to Development of Renal Flares: Results from Three Phase III Clinical Trials of Belimumab
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DOI: 10.3390/ijms232213941
Abstract: Renal flares constitute major determinants of poor prognosis in people living with systemic lupus erythematosus (SLE). The aim of the present study was to investigate changes in B cell subsets in relation to renal flares… read more here.
Keywords: renal flares; plasma cells; lived plasma; therapy ... See more keywords