Survival Benefit of Living-Donor Liver Transplant
Sign Up to like & getrecommendations! Published in 2022 at "JAMA Surgery"
DOI: 10.1001/jamasurg.2022.3327
Abstract: Key Points Question Compared with the wait list, what is the survival benefit of a living-donor liver transplant for patients with end-stage liver disease based on patients’ Model for End-stage Liver Disease incorporating sodium levels… read more here.
Keywords: survival benefit; liver transplant; liver; living donor ... See more keywords
Egr‐1 transcriptionally activates protein phosphatase PTP1B to facilitate hyperinsulinemia‐induced insulin resistance in the liver in type 2 diabetes
Sign Up to like & getrecommendations! Published in 2019 at "FEBS Letters"
DOI: 10.1002/1873-3468.13537
Abstract: During the development of type 2 diabetes mellitus (T2DM), hyperinsulinemia is the earliest symptom. It is believed that long‐term high insulin stimulation might facilitate insulin resistance in the liver, but the underlying mechanism remains unknown.… read more here.
Keywords: resistance liver; hyperinsulinemia; liver; type diabetes ... See more keywords
A knowledge‐based approach to automated planning for hepatocellular carcinoma
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Applied Clinical Medical Physics"
DOI: 10.1002/acm2.12219
Abstract: Abstract Purpose To build a knowledge‐based model of liver cancer for Auto‐Planning, a function in Pinnacle, which is used as an automated inverse intensity modulated radiation therapy (IMRT) planning system. Methods and Materials Fifty Tomotherapy… read more here.
Keywords: planning; liver; model; knowledge based ... See more keywords
Retrospective four‐dimensional magnetic resonance imaging of liver: Method development
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Applied Clinical Medical Physics"
DOI: 10.1002/acm2.13108
Abstract: Abstract Purpose of our research was to develop a four‐dimensional (4D) magnetic resonance imaging (MRI) method of liver. Requirements of the method were to create a clinical procedure with acceptable imaging time and sufficient temporal… read more here.
Keywords: resonance imaging; magnetic resonance; four dimensional; method ... See more keywords
Evaluation of Atlas‐based auto‐segmentation of liver in MR images for Yttrium‐90 selective internal radiation therapy
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Applied Clinical Medical Physics"
DOI: 10.1002/acm2.13979
Abstract: Abstract Purpose The aim was to explore the feasibility of applying an atlas‐based auto‐segmentation tool, MIM Atlas Segment, for liver delineation in MR images in Y‐90 selective internal radiation therapy (SIRT). Materials and methods MR… read more here.
Keywords: liver; auto; auto segmentation; atlas based ... See more keywords
Bioinspired Artificial Liver System with hiPSC-derived Hepatocytes for Acute Liver Failure Treatment.
Sign Up to like & getrecommendations! Published in 2021 at "Advanced healthcare materials"
DOI: 10.1002/adhm.202101580
Abstract: Bioartificial liver (BAL) system has become a promising alternative to traditional liver transplantation in rescuing acute liver failure (ALF) patients. Herein, inspired by natural microstructure of hepatic lobules, we developed a novel biomimetic bioartificial liver… read more here.
Keywords: derived hepatocytes; liver failure; system; acute liver ... See more keywords
Decellularized Liver Nanofibers Enhance and Stabilize the Long-term Functions of Primary Human Hepatocytes In Vitro.
Sign Up to like & getrecommendations! Published in 2023 at "Advanced healthcare materials"
DOI: 10.1002/adhm.202202302
Abstract: Owing to significant differences across species in liver functions, in vitro human liver models are used for screening the metabolism and toxicity of compounds, modeling diseases, and cell-based therapies. However, the extracellular matrix (ECM) scaffold… read more here.
Keywords: human hepatocytes; liver; primary human; topography ... See more keywords
A Biomimetic Nanoparticle Exerting Protection Against Acute Liver Failure by Suppressing CYP2E1 Activity and Scavenging Excessive ROS.
Sign Up to like & getrecommendations! Published in 2023 at "Advanced healthcare materials"
DOI: 10.1002/adhm.202300571
Abstract: Acute liver failure (ALF) is a severe liver disease caused by many reasons. One of them is the overdosed acetaminophen (APAP), which is metabolized into N-acetyl-p-benzoquinone imine (NAPQI), an excessive toxic metabolite, by CYP2E1, resulting… read more here.
Keywords: cyp2e1; liver; liver failure; acute liver ... See more keywords
Microfluidic controllable preparation of iodine-131-labeled microspheres for radioembolization therapy of liver tumors.
Sign Up to like & getrecommendations! Published in 2023 at "Advanced healthcare materials"
DOI: 10.1002/adhm.202300873
Abstract: Transcatheter arterial radioembolization (TARE) is of great significance for the treatment of advanced hepatocellular carcinoma (HCC). However, the existing radioembolic microspheres still have problems such as non-degradability, non-uniform size, and inability to directly monitor in… read more here.
Keywords: liver; microfluidic controllable; 131 labeled; 131 gms ... See more keywords
Understanding Nanomaterial–Liver Interactions to Facilitate the Development of Safer Nanoapplications
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Materials"
DOI: 10.1002/adma.202106456
Abstract: Nanomaterials (NMs) are widely used in commercial and medical products, such as cosmetics, vaccines, and drug carriers. Exposure to NMs via various routes such as dermal, inhalation, and ingestion has been shown to gain access… read more here.
Keywords: development safer; liver; facilitate development; liver interactions ... See more keywords
Multi‐Targeted Peptide‐Modified Gold Nanoclusters for Treating Solid Tumors in the Liver
Sign Up to like & getrecommendations! Published in 2023 at "Advanced Materials"
DOI: 10.1002/adma.202210412
Abstract: Apoptosis and autophagy determine the fate of cancer cells. However, simply promoting apoptosis of tumor cells is limited in the treatment of unresectable solid liver tumors. Generally, autophagy is considered the anti‐apoptotic “guardian”. But the… read more here.
Keywords: modified gold; liver; liver tumors; peptide modified ... See more keywords