An mtDNA mutation accelerates liver aging by interfering with the ROS response and mitochondrial life cycle
Sign Up to like & getrecommendations! Published in 2017 at "Free Radical Biology and Medicine"
DOI: 10.1016/j.freeradbiomed.2016.11.035
Abstract: Abstract Mitochondrial dysfunction affects liver metabolism, but it remains unclear whether this interferes with normal liver aging. We investigated several mitochondrial pathways in hepatocytes and liver tissue from a conplastic mouse strain compared with the… read more here.
Keywords: liver aging; response; c57bl 6ntac; 6ntac mtnodltj ... See more keywords
Aging and Aging-Related Senescence in Liver
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DOI: 10.1055/a-2637-2549
Abstract: Abstract Aging is characterized by the progressive deterioration of cell and tissue functions. The liver, which regulates metabolic homeostasis, detoxification, and immune responses, undergoes structural and functional changes with age. These include increasing genomic instability,… read more here.
Keywords: senescence; liver aging; aging aging; aging related ... See more keywords
Green Tea Polyphenols Upregulate the Nrf2 Signaling Pathway and Suppress Oxidative Stress and Inflammation Markers in D-Galactose-Induced Liver Aging in Mice
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Nutrition"
DOI: 10.3389/fnut.2022.836112
Abstract: The beneficial effects of green tea polyphenols (GTPs) on D-galactose (D-Gal)-induced liver aging in male Kunming mice were investigated. For this purpose, 40 adult male Kunming mice were divided into four groups. All animals, except… read more here.
Keywords: tea polyphenols; green tea; mice; oxidative stress ... See more keywords
Regulation of Circadian Genes Nr1d1 and Nr1d2 in Sex-Different Manners during Liver Aging
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DOI: 10.3390/ijms231710032
Abstract: Background: Circadian rhythm is associated with the aging process and sex differences; however, how age and sex can change circadian regulation systems remains unclear. Thus, we aimed to evaluate age- and sex-related changes in gene… read more here.
Keywords: expression; circadian genes; sex; liver aging ... See more keywords