Standardizing the histological assessment of late posttransplantation biopsies from pediatric liver allograft recipients
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DOI: 10.1002/lt.26482
Abstract: Excellent short‐term survival after pediatric liver transplantation (LT) has shifted attention toward the optimization of long‐term outcomes. Despite considerable progress in imaging and other noninvasive modalities, liver biopsies continue to be required to monitor allograft… read more here.
Keywords: assessment late; assessment; standardizing histological; liver allograft ... See more keywords
Deceased Donor Predictors for Pediatric Liver Allograft Utilization.
Sign Up to like & getrecommendations! Published in 2020 at "Transplantation proceedings"
DOI: 10.1016/j.transproceed.2020.05.010
Abstract: BACKGROUND The number of pediatric deceased organ donors has recently declined, and the nonutilization of pediatric liver allografts has limited the development of liver transplantation. We determined the utilization rate of pediatric livers and identified… read more here.
Keywords: utilization; risk factors; allograft utilization; liver allograft ... See more keywords
Late-Onset Rejection in Liver Allograft Biopsies.
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DOI: 10.1093/ajcp/aqac162
Abstract: OBJECTIVES Both alloimmune and nonalloimmune factors affect the long-term survival of liver allograft recipients. Various patterns of late-onset rejection are recognized, including typical acute cellular rejection (tACR), ductopenic rejection (DuR), nonspecific hepatitis (NSH), isolated central… read more here.
Keywords: liver allograft; onset rejection; rejection; late onset ... See more keywords
Recurrent Idiopathic Liver Allograft Failure.
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DOI: 10.1093/ajcp/aqz044
Abstract: OBJECTIVES Many transplant programs have had patients who develop idiopathic recurrent liver allograft failure, necessitating serial transplants, and are deemed to have refractory or recurrent rejection. The frequency and the etiology of this immunologic dysfunction… read more here.
Keywords: liver allograft; failure; recurrent; allograft failure ... See more keywords
Predicting Liver Allograft Discard: The Discard Risk Index
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DOI: 10.1097/tp.0000000000002151
Abstract: Background An index that predicts liver allograft discard can effectively grade allografts and can be used to preferentially allocate marginal allografts to aggressive centers. The aim of this study is to devise an index to… read more here.
Keywords: liver allograft; allograft discard; risk; index ... See more keywords
Short‐term therapy with anti‐ICAM‐1 monoclonal antibody induced long‐term liver allograft survival in nonhuman primates
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DOI: 10.1111/ajt.16486
Abstract: Tolerance induction remains challenging following liver transplantation and the long‐term use of immunosuppressants, especially calcineurin inhibitors, leads to serious complications. We aimed to test an alternative immunosuppressant, a chimeric anti‐ICAM‐1 monoclonal antibody, MD‐3, for improving… read more here.
Keywords: allograft survival; term; antibody; liver ... See more keywords
The impact of donor liver allograft fibrosis on patients undergoing liver transplantation
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DOI: 10.1111/ctr.13187
Abstract: The utilization of extended criteria liver allografts (ECD) shortens time to transplantation. read more here.
Keywords: impact donor; transplantation impact; allograft fibrosis; transplantation ... See more keywords
Morphologic and immunophenotypic evaluation of liver allograft biopsies with contemporaneous serum DSA measurements.
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DOI: 10.1111/ctr.14997
Abstract: BACKGROUND Acute antibody mediated rejection is increasingly identified in liver allografts as a unique form of alloimmune injury associated with donor specific antibodies (DSA). This manifests pathologically as microvascular injury and C4d uptake. Despite the… read more here.
Keywords: liver allograft; dsa positive; dsa; serum dsa ... See more keywords