Activation of Liver AMPK with PF-06409577 Corrects NAFLD and Lowers Cholesterol in Rodent and Primate Preclinical Models
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DOI: 10.1016/j.ebiom.2018.04.009
Abstract: Dysregulation of hepatic lipid and cholesterol metabolism is a significant contributor to cardiometabolic health, resulting in excessive liver lipid accumulation and ultimately non-alcoholic steatohepatitis (NASH). Therapeutic activators of the AMP-Activated Protein Kinase (AMPK) have been… read more here.
Keywords: liver ampk; cholesterol; lipid cholesterol; ampk 06409577 ... See more keywords