Systemic Metabolic Alteration Dependent on the Thyroid‐Liver Axis in Early PD
Sign Up to like & getrecommendations! Published in 2022 at "Annals of Neurology"
DOI: 10.1002/ana.26510
Abstract: Parkinson's disease (PD) is a common neurodegenerative disease characterized by initial involvement of the olfactory bulb/amygdala or autonomic nerves followed by nigral degeneration. Although autonomic innervation strictly regulates multiorgan systems, including endocrine functions, circulation, and… read more here.
Keywords: thyroid liver; metabolic alteration; dependent thyroid; systemic metabolic ... See more keywords
Examining the gut-liver axis in liver cancer using organoid models.
Sign Up to like & getrecommendations! Published in 2021 at "Cancer letters"
DOI: 10.1016/j.canlet.2021.04.008
Abstract: The World Health Organization predicts that by 2030 liver cancer will cause 1 million deaths annually, thus becoming the third most lethal cancer worldwide. Hepatocellular carcinoma and cholangiocarcinoma are the two major primary cancer subtypes… read more here.
Keywords: gut liver; liver; liver axis; cancer ... See more keywords
Contribution of the gut microbiota to the regulation of host metabolism and energy balance: a focus on the gut–liver axis
Sign Up to like & getrecommendations! Published in 2019 at "Proceedings of the Nutrition Society"
DOI: 10.1017/s0029665118002756
Abstract: This review presents mechanistic studies performed in vitro and in animal models, as well as data obtained in patients that contribute to a better understanding of the impact of nutrients interacting with the gut microbiota… read more here.
Keywords: liver axis; metabolism; gut liver; gut microbiota ... See more keywords
Novel Strategy for Validating the Existence and Mechanism of the "gut-liver axis" in Vivo by a Hypoxia-Sensitive NIR Fluorescent Probe.
Sign Up to like & getrecommendations! Published in 2020 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.9b04578
Abstract: Liver fibrosis is a major stage in the development of liver diseases and it is important to investigate its pathogenesis for early intervene or even reversing. Recent studies have found that intestinal disease can aggravate… read more here.
Keywords: gut liver; probe; liver; liver axis ... See more keywords
Propionate Ameliorates Alcohol-Induced Liver Injury in Mice via the Gut-Liver Axis: Focus on the Improvement of Intestinal Permeability.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.2c00633
Abstract: Alcohol-related liver disease (ALD) is a major cause of chronic liver disease worldwide with limited therapeutic options. Here, we first revealed the promising beneficial effect of gut microbiota-derived propionate on alcoholic liver injury in mice.… read more here.
Keywords: gut; injury mice; liver injury; mice ... See more keywords
Ameliorative Effect of Chitosan Oligosaccharides on Hepatic Encephalopathy by Reshaping Gut Microbiota and Gut-Liver Axis.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.2c01330
Abstract: This study investigated the influence of chitosan oligosaccharides (COSs) on a thioacetamide-induced hepatic encephalopathy (HE) Wistar rat model. COS treatment statistically reduced the false neurotransmitters and blood ammonia in HE rats, along with the suppression… read more here.
Keywords: hepatic encephalopathy; chitosan oligosaccharides; gut; gut microbiota ... See more keywords
Phytic Acid Improves Hepatic Steatosis, Inflammation, and Oxidative Stress in High-Fat Diet (HFD)-Fed Mice by Modulating the Gut-Liver Axis.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.2c04406
Abstract: Nonalcoholic fatty liver disease (NAFLD) induced by obesity is a grave threat to human health. Phytic acid (PA) is a natural compound found in high-fiber diets, such as soybeans. This study investigated the effects and… read more here.
Keywords: inflammation; liver; gut; hfd ... See more keywords
Conditioned medium from stem cells derived from human exfoliated deciduous teeth ameliorates NASH via the Gut-Liver axis
Sign Up to like & getrecommendations! Published in 2021 at "Scientific Reports"
DOI: 10.1038/s41598-021-98254-8
Abstract: Non-alcoholic steatohepatitis (NASH) occurrence has been increasing and is becoming a major cause of liver cirrhosis and liver cancer. However, effective treatments for NASH are still lacking. We examined the benefits of serum-free conditioned medium… read more here.
Keywords: conditioned medium; medium stem; gut liver; liver ... See more keywords
NAFLD and the Gut-Liver Axis: Exploring an Undernutrition Perspective.
Sign Up to like & getrecommendations! Published in 2022 at "Gastroenterology"
DOI: 10.1053/j.gastro.2022.01.058
Abstract: Non-alcoholic fatty liver disease (NAFLD) is a chronic condition affecting one quarter of the global population. Although primarily linked to obesity and metabolic syndrome, undernutrition and the altered (dysbiotic) gut microbiome influence NAFLD progression. Both… read more here.
Keywords: undernutrition; gut; axis exploring; nafld gut ... See more keywords
SARS-CoV-2 infection and the gut-liver axis.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of digestive diseases"
DOI: 10.1111/1751-2980.12951
Abstract: Patients affected with Covid-19 that is caused by the severe acute respiratory syndrome coronavirus 2, manifest various gastrointestinal and hepatic abnormalities alongside respiratory disorder. The identification of this virus in the feces of more than… read more here.
Keywords: gut liver; liver axis; sars cov; cov infection ... See more keywords
Brain–liver axis: a new pathway for cognitive disorders related to hepatic fibrosis
Sign Up to like & getrecommendations! Published in 2020 at "European Journal of Neurology"
DOI: 10.1111/ene.14454
Abstract: The brain is not the central organ, isolated in its skull that we usually imagine. It is connected to many other organs including the liver. Brain-liver relationships result from metabolic, hormonal, immunological or inflammatory pathways. read more here.
Keywords: axis new; pathway cognitive; brain liver; liver axis ... See more keywords