Drinking for protection? Epidemiological and experimental evidence on the beneficial effects of coffee or major coffee compounds against gastrointestinal and liver carcinogenesis.
Sign Up to like & getrecommendations! Published in 2019 at "Food research international"
DOI: 10.1016/j.foodres.2019.05.029
Abstract: Recent meta-analyses indicate that coffee consumption reduces the risk for digestive tract (oral, esophageal, gastric and colorectal) and, especially, liver cancer. Coffee bean-derived beverages, as the widely-consumed espresso and "common" filtered brews, present remarkable historical,… read more here.
Keywords: gastrointestinal liver; epidemiological experimental; beneficial effects; effects coffee ... See more keywords
Alcohol and its associated liver carcinogenesis.
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DOI: 10.1111/jgh.16248
Abstract: Alcohol consumption is a major cause of cirrhosis and hepatocellular carcinoma (HCC). The prevalence of alcohol-associated hepatocellular carcinoma (aHCC) varies worldwide but is highest in Eastern Europe. Alcohol is the second fastest-growing cause of age-standardized… read more here.
Keywords: associated liver; alcohol associated; hepatology; alcohol ... See more keywords
Constitutive Activation of the Tumor Suppressor p53 in Hepatocytes Paradoxically Promotes Non–Cell Autonomous Liver Carcinogenesis
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DOI: 10.1158/0008-5472.can-21-4390
Abstract: This study reveals that activation of p53 in hepatocytes promotes liver carcinogenesis derived from HPCs, which elucidates a paradoxical aspect of a tumor suppressor p53 and novel mechanism of liver carcinogenesis. read more here.
Keywords: p53 hepatocytes; tumor suppressor; suppressor p53; p53 ... See more keywords
The emerging roles of m6A modification in liver carcinogenesis
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DOI: 10.7150/ijbs.50003
Abstract: The 'epitranscriptome', a collective term for chemical modifications that influence the structure, metabolism, and functions of RNA, has recently emerged as vitally important for the regulation of gene expression. N6-methyladenosine (m6A), the most prevalent mammalian… read more here.
Keywords: modification liver; liver carcinogenesis; modification; m6a modification ... See more keywords