Comparing the lipogenic and cholesterolgenic effects of individual trans‐18:1 isomers in liver cells
Sign Up to like & getrecommendations! Published in 2017 at "European Journal of Lipid Science and Technology"
DOI: 10.1002/ejlt.201600162
Abstract: The present study compared the lipogenic/cholesterolgenic effects of t6-, t9- (positive control), t10-, t11-, t13-, t14-, t15-18:1, cis(c)9-18:1 (cis control) or bovine serum albumin (BSA; negative control) in liver cells (HepG2). Fatty acids (100 μM) were… read more here.
Keywords: control; fatty acid; t18 isomers; cholesterolgenic effects ... See more keywords
Exploring the interactions between polyunsaturated fatty acids and cadmium in rainbow trout liver cells: a genetic and proteomic study.
Sign Up to like & getrecommendations! Published in 2018 at "Aquatic toxicology"
DOI: 10.1016/j.aquatox.2018.09.005
Abstract: Polyunsaturated fatty acids (PUFAs) have key biological roles in fish cells. We recently showed that the phospholipid composition of rainbow trout liver cells (RTL-W1 cell line) modulates their tolerance to an acute cadmium (Cd) challenge.… read more here.
Keywords: polyunsaturated fatty; fatty acid; fatty acids; liver cells ... See more keywords
A mass spectrometry-based strategy combined with bioinformatics: A simple preclinical model for profiling valproic-acid-induced major proteins and modifications in human liver cells
Sign Up to like & getrecommendations! Published in 2017 at "Process Biochemistry"
DOI: 10.1016/j.procbio.2017.04.021
Abstract: Abstract The clinical use of valproic acid (VA) as an antiepileptic drug is associated with adverse effects such as hepatotoxicity and encephalopathy. These potential complications may be caused by reactive oxygen species (ROS) produced during… read more here.
Keywords: mass spectrometry; valproic acid; liver cells; human liver ... See more keywords
An eight-compound mixture but not corresponding concentrations of individual chemicals induces triglyceride accumulation in human liver cells.
Sign Up to like & getrecommendations! Published in 2021 at "Toxicology"
DOI: 10.1016/j.tox.2021.152857
Abstract: In real life, organisms are exposed to complex mixtures of chemicals at low concentration levels, whereas research on toxicological effects is mostly focused on single compounds at comparably high doses. Mixture effects deviating from the… read more here.
Keywords: accumulation; triglyceride accumulation; compound; liver cells ... See more keywords
Transcriptional Inhibition of MicroRNA miR-122 by Small Molecules Reduces Hepatitis C Virus Replication in Liver Cells.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of medicinal chemistry"
DOI: 10.1021/acs.jmedchem.2c01141
Abstract: MicroRNAs (miRNAs) are noncoding RNA molecules of 22-24 nucleotides that are estimated to regulate thousands of genes in humans, and their dysregulation has been implicated in many diseases. MicroRNA-122 (miR-122) is the most abundant miRNA… read more here.
Keywords: liver; mir 122; liver cells; hepatitis virus ... See more keywords
Effects of Polystyrene Microplastics on Human Kidney and Liver Cell Morphology, Cellular Proliferation, and Metabolism
Sign Up to like & getrecommendations! Published in 2022 at "ACS Omega"
DOI: 10.1021/acsomega.2c03453
Abstract: Microplastics have gained much attention due to their prevalence and abundance in our everyday lives. They have been detected in household items such as sugar, salt, honey, seafood, tap water, water bottles, and food items… read more here.
Keywords: cell; liver; human kidney; liver cells ... See more keywords
Genotoxic response of blood, gill and liver cells of Piaractus mesopotamicus after an acute exposure to a glyphosate-based herbicide
Sign Up to like & getrecommendations! Published in 2017 at "Caryologia"
DOI: 10.1080/00087114.2016.1254454
Abstract: Abstract The use of pesticides may affect the aquatic ecosystem. Through soil, these contaminants are drained into rivers. In South America, glyphosate-base herbicides, such as Roundup, are widely used in agricultural activities. In this work,… read more here.
Keywords: piaractus mesopotamicus; gill liver; blood gill; glyphosate ... See more keywords
L-Ascorbic Acid and α-Tocopherol Reduces Hepatotoxicity Associated with Arsenic Trioxide Chemotherapy by Modulating Nrf2 and Bcl2 Transcription Factors in Chang liver Cells
Sign Up to like & getrecommendations! Published in 2018 at "Nutrition and Cancer"
DOI: 10.1080/01635581.2018.1460676
Abstract: ABSTRACT Arsenic trioxide (As2O3) is a promising new regimen for the treatment of acute promyelocytic leukemia (APL). The induction of oxidative stress mediated by reactive oxygen species (ROS) and excessive intracellular calcium influx are the… read more here.
Keywords: chang liver; arsenic trioxide; acid tocopherol; ascorbic acid ... See more keywords
Potential threat of Chlorpyrifos to human liver cells via the caspase-dependent mitochondrial pathways
Sign Up to like & getrecommendations! Published in 2018 at "Food and Agricultural Immunology"
DOI: 10.1080/09540105.2017.1373271
Abstract: ABSTRACT Chlorpyrifos (CPF) has been widely used around the world as a pesticide for both agricultural and residential application. Although various studies have reported toxicity and health-related effects from CPF exposure, the potential threat and… read more here.
Keywords: dependent mitochondrial; caspase dependent; liver; potential threat ... See more keywords
Intrahepatic and peripheral blood phenotypes of natural killer and T cells: differential surface expression of killer cell immunoglobulin‐like receptors
Sign Up to like & getrecommendations! Published in 2018 at "Immunology"
DOI: 10.1111/imm.12880
Abstract: Deep characterization of the frequencies, phenotypes and functionalities of liver and peripheral blood natural killer (NK), natural killer T (NKT) and T cells from healthy individuals is an essential step to further interpret changes in… read more here.
Keywords: killer; natural killer; peripheral blood; expression ... See more keywords
Advances on liver cell‐derived exosomes in liver diseases
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Cellular and Molecular Medicine"
DOI: 10.1111/jcmm.16123
Abstract: Exosomes are extracellular vesicles with diameters ranging from 30 to 150 nm, which contain several donor cell‐associated proteins as well as mRNA, miRNA, and lipids and coordinate multiple physiological and pathological functions through horizontal communication… read more here.
Keywords: liver cell; cell derived; liver diseases; liver ... See more keywords