Modulatory effect of Cyclocarya paliurus flavonoids on the intestinal microbiota and liver clock genes of circadian rhythm disorder mice model.
Sign Up to like & getrecommendations! Published in 2020 at "Food research international"
DOI: 10.1016/j.foodres.2020.109769
Abstract: Host circadian rhythm and gut microbiota have a bidirectional relationship, indicating that prebiotics or prebiotic-like substance is a possible way to regulate circadian rhythm. The modulatory effect of Cyclocarya paliurus flavonoids (CPF) on the intestinal… read more here.
Keywords: rhythm; rhythm disorder; circadian rhythm; clock genes ... See more keywords
Oolong tea polyphenols ameliorate circadian rhythm of intestinal microbiome and liver clock genes in mouse model.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.9b04869
Abstract: Our present study focused on the regulating effect of oolong tea polyphenols (OTP) on the circadian rhythm of liver and intestinal microbiome. OTP significantly alleviated the disrupted diurnal oscillation and phase shift of the specific… read more here.
Keywords: intestinal microbiome; rhythm; circadian rhythm; oolong tea ... See more keywords
Diclofenac Disrupts the Circadian Clock and through Complex Cross-Talks Aggravates Immune-Mediated Liver Injury—A Repeated Dose Study in Minipigs for 28 Days
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24021445
Abstract: Diclofenac effectively reduces pain and inflammation; however, its use is associated with hepato- and nephrotoxicity. To delineate mechanisms of injury, we investigated a clinically relevant (3 mg/kg) and high-dose (15 mg/kg) in minipigs for 4… read more here.
Keywords: circadian clock; study; liver clock; diclofenac disrupts ... See more keywords