Regulation of radiation‐induced liver damage by modulation of SIRT‐1 activity: In vivo rat model
Sign Up to like & getrecommendations! Published in 2022 at "Cell Biochemistry and Function"
DOI: 10.1002/cbf.3762
Abstract: Silent information regulator 1 (SIRT‐1), a nicotinamide adenine dinucleotide‐dependent deacetylase, was found to regulate cell apoptosis, inflammation, and oxidative stress response in living organisms. Therefore, the role of SIRT‐1 in regulating forkhead box O/poly ADP‐ribose… read more here.
Keywords: liver damage; sirt activity; sirt; activity ... See more keywords
Dimethyl fumarate protects thioacetamide‐induced liver damage in rats: Studies on Nrf2, NLRP3, and NF‐κB
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Biochemical and Molecular Toxicology"
DOI: 10.1002/jbt.22476
Abstract: The present study was designed to investigate the hepatoprotective potential of dimethyl fumarate (DMF) against thioacetamide (TAA)‐induced liver damage. Wistar rats were treated with DMF (12.5, 25, and 50 mg/kg/day, orally) and TAA (200 mg/kg intraperitoneally, every… read more here.
Keywords: induced liver; liver damage; taa induced; dimethyl fumarate ... See more keywords
Comparison between the effects of selenomethionine and S-adenosylmethionine in preventing cholestasis-induced rat liver damage
Sign Up to like & getrecommendations! Published in 2019 at "Amino Acids"
DOI: 10.1007/s00726-019-02716-3
Abstract: We aimed to evaluate whether two methionine-related compounds, S-adenosylmethionine (SAM), and selenomethionine (SM), could lessen liver damage induced by regurgitated bile in a model of rat bile duct ligation (BDL). Hepatoprotective potentials of S-adenosylmethionine and… read more here.
Keywords: liver damage; activity; rat; damage ... See more keywords
Assessing the potential value of Rosa Roxburghii Tratt in arsenic-induced liver damage based on elemental imbalance and oxidative damage
Sign Up to like & getrecommendations! Published in 2020 at "Environmental Geochemistry and Health"
DOI: 10.1007/s10653-020-00612-4
Abstract: Environmental exposure to arsenic is a major public health challenge worldwide. Growing evidence indicates that coal-burning arsenic can cause hepatic oxidative damage. However, the value of Rosa roxburghii Tratt (RRT) with antioxidant properties on arsenic-caused… read more here.
Keywords: oxidative damage; liver damage; arsenic induced; damage ... See more keywords
Albumin binding function is a novel biomarker for early liver damage and disease progression in non-alcoholic fatty liver disease
Sign Up to like & getrecommendations! Published in 2020 at "Endocrine"
DOI: 10.1007/s12020-020-02319-z
Abstract: Purpose Indicators to assess early liver damage and disease progression in nonalcoholic fatty liver disease (NAFLD) remain unsatisfactory. Albumin binding function has been reported to be an early indicator of liver damage in hepatitis and… read more here.
Keywords: albumin binding; liver damage; disease; binding function ... See more keywords
Effects of multi-species probiotic supplementation on alcohol metabolism in rats.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of microbiology"
DOI: 10.1007/s12275-021-0573-2
Abstract: Probiotics are known to protect against liver damage induced by the alcohol and acetaldehyde accumulation associated with alcohol intake. However, there have been few studies of the direct effect of probiotics on alcohol metabolism, and… read more here.
Keywords: alcohol metabolism; alcohol acetaldehyde; liver damage; alcohol ... See more keywords
The Therapeutic Potential of Extracellular Vesicles Versus Mesenchymal Stem Cells in Liver Damage
Sign Up to like & getrecommendations! Published in 2020 at "Tissue Engineering and Regenerative Medicine"
DOI: 10.1007/s13770-020-00267-3
Abstract: Background: The extracellular vesicles (EVs) secreted by bone marrow-derived mesenchymal stem cells (MSCs) hold significant potential as a novel alternative to whole-cell therapy. We herein compare the therapeutic potential of BM-MSCs versus their EVs (MSC-EVs)… read more here.
Keywords: extracellular vesicles; liver damage; mscs; therapeutic potential ... See more keywords
Feminization, altered gonadal development, and liver damage in least killifish (Heterandria formosa) exposed to sublethal concentrations of 17α-ethinylestradiol.
Sign Up to like & getrecommendations! Published in 2019 at "Ecotoxicology and environmental safety"
DOI: 10.1016/j.ecoenv.2018.11.094
Abstract: The widespread use of the synthetic estrogen 17 α-ethinylestradiol (EE2) has resulted in elevated levels in aquatic environments, where it is known to act as an endocrine disrupting chemical affecting fish and other aquatic organisms.… read more here.
Keywords: least killifish; liver damage; heterandria formosa; development ... See more keywords
Complement regulatory protein CD59a plays a protective role in immune liver injury of trichloroethylene-sensitized BALB/c mice.
Sign Up to like & getrecommendations! Published in 2019 at "Ecotoxicology and environmental safety"
DOI: 10.1016/j.ecoenv.2019.01.049
Abstract: Trichloroethylene (TCE) is a major occupational and environmental chemical compound which causes occupational dermatitis medicamentosa-like of TCE with severe liver damage. Our previous studies showed that complement activation was a newly recognized mechanism for TCE-induced… read more here.
Keywords: tce; liver damage; balb mice; immune liver ... See more keywords
Excessive ammonia inhalation causes liver damage and dysfunction by altering gene networks associated with oxidative stress and immune function.
Sign Up to like & getrecommendations! Published in 2021 at "Ecotoxicology and environmental safety"
DOI: 10.1016/j.ecoenv.2021.112203
Abstract: Ammonia (NH3) is a major gaseous pollutant in livestock production and has adverse effects on production, health and welfare of animals. The liver is one of the target organs of NH3, and excessive NH3 inhalation… read more here.
Keywords: nh3; liver damage; inhalation; function ... See more keywords
Combination therapy of Juzentaihoto and mesenchymal stem cells attenuates liver damage and regresses fibrosis in mice
Sign Up to like & getrecommendations! Published in 2021 at "Regenerative Therapy"
DOI: 10.1016/j.reth.2021.07.002
Abstract: Background Liver cirrhosis is an end-stage multiple liver disease. Mesenchymal stem cells (MSCs) are an attractive cell source for reducing liver damage and regressing fibrosis; additional therapies accompanying MSCs can potentially enhance their therapeutic effects.… read more here.
Keywords: combination therapy; liver damage; jtt; damage ... See more keywords