Fabrication of liver-derived extracellular matrix nanofibers and functional evaluation in in vitro culture using primary hepatocytes
Sign Up to like & getrecommendations! Published in 2018 at "Materialia"
DOI: 10.1016/j.mtla.2018.11.014
Abstract: Abstract Fabrication of functional scaffolds is one of the main goals of tissue engineering, particularly scaffolds mimicking the native extracellular matrix (ECM) and stimulating a microenvironment that supports cell growth and function. In this study,… read more here.
Keywords: extracellular matrix; liver derived; vitro culture; primary hepatocytes ... See more keywords
Recapitulating hepatitis E virus–host interactions and facilitating antiviral drug discovery in human liver–derived organoids
Sign Up to like & getrecommendations! Published in 2022 at "Science Advances"
DOI: 10.1126/sciadv.abj5908
Abstract: Hepatotropic viruses naturally have narrow host and tissue tropisms, challenging the development of robust experimental models. The advent of organoid technology provides a unique opportunity for moving the field forward. Here, we demonstrate that three-dimensional… read more here.
Keywords: derived organoids; liver derived; hev; human liver ... See more keywords
Insight into the Inter-Organ Crosstalk and Prognostic Role of Liver-Derived MicroRNAs in Metabolic Disease Progression
Sign Up to like & getrecommendations! Published in 2023 at "Biomedicines"
DOI: 10.3390/biomedicines11061597
Abstract: Dysfunctional hepatic metabolism has been linked to numerous diseases, including non-alcoholic fatty liver disease, the most common chronic liver disorder worldwide, which can progress to hepatic fibrosis, and is closely associated with insulin resistance and… read more here.
Keywords: liver; disease; liver derived; metabolic disease ... See more keywords
Lysophosphatidylethanolamine Affects Lipid Accumulation and Metabolism in a Human Liver-Derived Cell Line
Sign Up to like & getrecommendations! Published in 2022 at "Nutrients"
DOI: 10.3390/nu14030579
Abstract: The physiological functions of lysophosphatidylethanolamine (lysoPE) have not been fully elucidated. In this study, the effects of lysoPE on lipogenesis and lipolysis were investigated in a cultured human liver-derived cell line. The intracellular lipid profile… read more here.
Keywords: lysope; derived cell; cell line; liver derived ... See more keywords
Liver-Derived Exosomes Induce Inflammation and Lipogenesis in Mice Fed High-Energy Diets
Sign Up to like & getrecommendations! Published in 2022 at "Nutrients"
DOI: 10.3390/nu14235124
Abstract: The liver is an endocrine organ and is the first organ exposed to nutrients when they are absorbed into the body before being metabolized by the distal organs. Although the liver plays an essential role… read more here.
Keywords: hfs group; liver derived; derived exosomes; inflammation lipogenesis ... See more keywords