Association of Weight Loss Interventions With Changes in Biomarkers of Nonalcoholic Fatty Liver Disease
Sign Up to like & getrecommendations! Published in 2019 at "JAMA Internal Medicine"
DOI: 10.1001/jamainternmed.2019.2248
Abstract: Key Points Question Are weight loss interventions associated with changes in biomarkers of liver disease in people with nonalcoholic fatty liver disease? Findings In this systematic review and meta-analysis of 22 randomized clinical trials with… read more here.
Keywords: nonalcoholic fatty; liver disease; weight loss; fatty liver ... See more keywords
Analysis of Severe Hypoglycemia Among Adults With Type 2 Diabetes and Nonalcoholic Fatty Liver Disease
Sign Up to like & getrecommendations! Published in 2022 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2022.0262
Abstract: Key Points Question Is nonalcoholic fatty liver disease (NAFLD) associated with severe hypoglycemia in individuals with type 2 diabetes? Findings In cohort study of more than 1.9 million individuals, participants with type 2 diabetes and… read more here.
Keywords: type diabetes; liver disease; fatty liver; severe hypoglycemia ... See more keywords
Evaluation of Early vs Standard Liver Transplant for Alcohol-Associated Liver Disease.
Sign Up to like & getrecommendations! Published in 2021 at "JAMA surgery"
DOI: 10.1001/jamasurg.2021.3748
Abstract: Importance Traditionally, liver transplant (LT) for alcohol-associated liver disease (ALD) requires 6 months of abstinence. Although early LT before 6 months of abstinence has been associated with decreased mortality for decompensated ALD, this practice remains… read more here.
Keywords: early standard; free survival; relapse free; liver disease ... See more keywords
Transcription factor SOX2 contributes to nonalcoholic fatty liver disease development by regulating the expression of the fatty acid transporter CD36
Sign Up to like & getrecommendations! Published in 2021 at "FEBS Letters"
DOI: 10.1002/1873-3468.14193
Abstract: Nonalcoholic fatty liver disease (NAFLD) can lead to hepatocellular carcinoma (HCC). The level of the transcription factor SOX2 correlates with HCC progression, but its role in fat accumulation remains unclear. Here, a high‐fat diet, with… read more here.
Keywords: fatty liver; cd36; transcription factor; sox2 ... See more keywords
Loss of EGFR contributes to high-fat diet-induced nonalcoholic fatty liver disease.
Sign Up to like & getrecommendations! Published in 2023 at "FEBS letters"
DOI: 10.1002/1873-3468.14636
Abstract: Using a murine model of high-fat diet (HFD)-induced non-alcoholic fatty liver disease (NAFLD), we found that the expression of the epidermal growth factor receptor (EGFR) significantly decreased in hepatocytes. In vitro, free fatty acid influx… read more here.
Keywords: fatty liver; high fat; egfr; liver disease ... See more keywords
Telomerase reverse transcriptase germline mutations and hepatocellular carcinoma in patients with nonalcoholic fatty liver disease
Sign Up to like & getrecommendations! Published in 2017 at "Cancer Medicine"
DOI: 10.1002/cam4.1078
Abstract: In an increasing proportion of cases, hepatocellular carcinoma (HCC) develops in patients with nonalcoholic fatty liver disease (NAFLD). Mutations in telomerase reverse transcriptase (hTERT) are associated with familial liver diseases. The aim of this study… read more here.
Keywords: liver disease; htert; nafld hcc; liver ... See more keywords
Alcoholic liver disease in relation to cancer incidence and mortality: Findings from a large, matched cohort study in South Korea
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Medicine"
DOI: 10.1002/cam4.5614
Abstract: To estimate the risk of cancer incidence and mortality among patients with alcoholic liver disease in South Korea. read more here.
Keywords: south korea; alcoholic liver; incidence mortality; liver disease ... See more keywords
Epigenetics and mitochondrial dysfunction insights into the impact of the progression of non‐alcoholic fatty liver disease
Sign Up to like & getrecommendations! Published in 2022 at "Cell Biochemistry and Function"
DOI: 10.1002/cbf.3763
Abstract: A metabolic problem occurs when regular functions of the body are disrupted due to an undesirable imbalance. Nonalcoholic fatty liver disease (NAFLD) is considered as one of the most common in this category. NAFLD is… read more here.
Keywords: fatty liver; disease; mitochondrial dysfunction; dysfunction insights ... See more keywords
Bile Acids, Gut Microbiome and the Road to Fatty Liver Disease.
Sign Up to like & getrecommendations! Published in 2021 at "Comprehensive Physiology"
DOI: 10.1002/cphy.c210024
Abstract: This article describes the complex interactions occurring between diet, the gut microbiome, and bile acids in the etiology of fatty liver disease. Perhaps 25% of the world's population may have nonalcoholic fatty liver disease (NAFLD)… read more here.
Keywords: liver disease; fatty liver; gut microbiome; bile acids ... See more keywords
Considerations for Physiologically Based Modeling in Liver Disease: From Nonalcoholic Fatty Liver (NAFL) to Nonalcoholic Steatohepatitis (NASH)
Sign Up to like & getrecommendations! Published in 2022 at "Clinical Pharmacology and Therapeutics"
DOI: 10.1002/cpt.2614
Abstract: Nonalcoholic fatty liver disease (NAFLD), representing a clinical spectrum ranging from nonalcoholic fatty liver (NAFL) to nonalcoholic steatohepatitis (NASH), is rapidly evolving into a global pandemic. Patients with NAFLD are burdened with high rates of… read more here.
Keywords: nonalcoholic fatty; liver nafl; fatty liver; pharmacology ... See more keywords
Angiotensin‐converting enzyme 2 inhibits endoplasmic reticulum stress–associated pathway to preserve nonalcoholic fatty liver disease
Sign Up to like & getrecommendations! Published in 2019 at "Diabetes/Metabolism Research and Reviews"
DOI: 10.1002/dmrr.3123
Abstract: Previous works indicated that the stress on the endoplasmic reticulum (ER) affected nonalcoholic fatty liver disease (NAFLD). However, there is no clear evident on the effect of the regulation of ER stress by angiotensin‐converting enzyme… read more here.
Keywords: fatty liver; endoplasmic reticulum; angiotensin converting; converting enzyme ... See more keywords