PTEN Down‐Regulation Promotes β‐Oxidation to Fuel Hypertrophic Liver Growth After Hepatectomy in Mice
Sign Up to like & getrecommendations! Published in 2017 at "Hepatology"
DOI: 10.1002/hep.29226
Abstract: In regenerating liver, hepatocytes accumulate lipids before the major wave of parenchymal growth. This transient, regeneration‐associated steatosis (TRAS) is required for liver recovery, but its purpose is unclear. The tumor suppressor phosphatase and tensin homolog… read more here.
Keywords: liver growth; oxidation; hypertrophic liver; liver ... See more keywords
A metabolomic approach shows sphingosine 1‐phosphate and lysophospholipids as mediators of the therapeutic effect of liver growth factor in emphysema
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Pharmaceutical and Biomedical Analysis"
DOI: 10.1016/j.jpba.2017.02.045
Abstract: HIGHLIGHTSMetabolomics study with plasma from mice exposed to tobacco smoke in an emphysema model.Liver growth factor could be useful to promote lung tissue regeneration.Lipid mediators, mainly sphingosine, sphingosine 1‐phosphate and lysophospholipids identified as markers.LC‐MS based… read more here.
Keywords: growth factor; sphingosine phosphate; factor; liver growth ... See more keywords
Blood flow forces liver growth
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DOI: 10.1038/d41586-018-06741-2
Abstract: Increases in biomechanical forces in the liver’s blood vessels have now been shown to activate two mechanosensitive proteins. The proteins trigger blood-vessel cells to deploy regenerative factors that drive liver growth.Mechanical forces on endothelial cells… read more here.
Keywords: blood flow; liver growth; flow forces; forces liver ... See more keywords
Protocol for a randomized controlled multicenter trial assessing the efficacy of leuprorelin for severe polycystic liver disease: the AGAINST-PLD study
Sign Up to like & getrecommendations! Published in 2022 at "BMC Gastroenterology"
DOI: 10.1186/s12876-022-02142-y
Abstract: Background In patients with severe polycystic liver disease (PLD), there is a need for new treatments. Estrogens and possibly other female sex hormones stimulate growth in PLD. In some patients, liver volume decreases after menopause.… read more here.
Keywords: study; liver growth; pld; trial ... See more keywords
Significance of Skeletal Muscle Loss in Liver Hypertrophy in Patients Undergoing Portal Vein Embolization Before Major Hepatectomy: Assessment With Body Composition and Nutritional Indicators
Sign Up to like & getrecommendations! Published in 2022 at "AntiCancer Research"
DOI: 10.21873/anticanres.16151
Abstract: Abstract Background/Aim: The relationship between body composition including skeletal muscle and liver hypertrophy initiated by portal vein embolization (PVE) for major hepatectomy has not been clarified. This study aimed to investigate the effects of skeletal… read more here.
Keywords: liver growth; skeletal muscle; muscle; liver hypertrophy ... See more keywords
The interplay between prenatal liver growth and lung development in congenital diaphragmatic hernia
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Pediatrics"
DOI: 10.3389/fped.2022.983492
Abstract: Objective Liver herniation is a known risk factor for increased severity in CDH and is associated with clinically significant pulmonary hypoplasia and pulmonary hypertension. Better studies are needed to understand the growth of the herniated… read more here.
Keywords: liver; lung development; growth; cdh ... See more keywords