A review of drug-induced liver injury databases
Sign Up to like & getrecommendations! Published in 2017 at "Archives of Toxicology"
DOI: 10.1007/s00204-017-2024-8
Abstract: Drug-induced liver injuries have been a major focus of current research in drug development, and are also one of the major reasons for the failure and withdrawal of drugs in development. Drug-induced liver injuries have… read more here.
Keywords: liver injuries; liver injury; drug induced; drug ... See more keywords
Long-Term Follow-Up After Non-operative Management of Blunt Splenic and Liver Injuries: A Questionnaire-Based Survey
Sign Up to like & getrecommendations! Published in 2017 at "World Journal of Surgery"
DOI: 10.1007/s00268-017-4336-5
Abstract: BackgroundNon-operative management (NOM) of blunt splenic or liver injuries (solid organ injury, SOI) has become the standard of care in hemodynamically stable patients. However, the incidence of long-term symptoms in these patients is currently not… read more here.
Keywords: term; liver injuries; blunt splenic; long term ... See more keywords
Mitochondria-Targetable Ratiometric Time-Gated Luminescence Probe Activated by Selenocysteine for the Visual Monitoring of Liver Injuries.
Sign Up to like & getrecommendations! Published in 2023 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.2c04409
Abstract: Liver injury can result from various risk factors including diabetes, virus, alcohol, drugs, and other toxins, which is mainly responsible for global mortality and morbidity. Selenocysteine (Sec), as the main undertaker of selenium function in… read more here.
Keywords: liver injury; mitochondria targetable; liver injuries; sec ... See more keywords
An observation-first strategy for liver injuries with “blush” on computed tomography is safe and effective
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Trauma and Acute Care Surgery"
DOI: 10.1097/ta.0000000000003786
Abstract: This important Western Trauma multicenter study found minimal benefit from embolization of liver injuries following the finding of blush on CT. Embolization carried a higher rate of complications with more drain placements and longer LOS.… read more here.
Keywords: liver; computed tomography; management; liver injuries ... See more keywords
Mouse Models of Liver Parenchyma Injuries and Regeneration
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DOI: 10.3389/fcell.2022.903740
Abstract: Mice have genetic and physiological similarities with humans and a well-characterized genetic background that is easy to manipulate. Murine models have become the most favored, robust mammalian systems for experimental analyses of biological processes and… read more here.
Keywords: mouse; models liver; murine models; liver injuries ... See more keywords
Deciphering the Underlying Mechanisms of Formula Le-Cao-Shi Against Liver Injuries by Integrating Network Pharmacology, Metabonomics, and Experimental Validation
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2022.884480
Abstract: Le-Cao-Shi (LCS) has long been used as a folk traditional Chinese medicine formula against liver injuries, whereas its pharmacological mechanisms remain elusive. Our study aims to investigate the underlying mechanism of LCS in treating liver… read more here.
Keywords: pharmacology; liver injuries; network pharmacology; metabolism ... See more keywords