Enzyme‐Responsive Nanoparachute for Targeted miRNA Delivery: A Protective Strategy Against Acute Liver and Kidney Injury (Adv. Sci. 10/2025)
Sign Up to like & getrecommendations! Published in 2025 at "Advanced Science"
DOI: 10.1002/advs.202570063
Abstract: Targeted miRNA Delivery The cover illustration features a tetrahedral‐framed spacecraft situated on a dune, which continues to interact with its base through its vertex components following disintegration. In article number 2411210 by Taoran Tian, Yunfeng… read more here.
Keywords: mirna delivery; strategy acute; targeted mirna; protective strategy ... See more keywords
Syringaldehyde Mitigates Cyclophosphamide‐Induced Liver and Kidney Toxicity in Mice by Inhibiting Oxidative Stress, Inflammation, and Apoptosis Through Modulation of the Nrf2/HO‐1/NFκB Pathway
Sign Up to like & getrecommendations! Published in 2025 at "Journal of Biochemical and Molecular Toxicology"
DOI: 10.1002/jbt.70172
Abstract: Cyclophosphamide (CYC) is one of the most potent antineoplastic drugs; however, hepatonephrotoxicity, observed following its use, remains one of its most severe side effects. Previous studies have reported that syringaldehyde (SYA), a flavonoid compound, exhibits… read more here.
Keywords: nrf2 pathway; hepatonephrotoxicity; oxidative stress; liver kidney ... See more keywords
Liver and/or kidney transplantation in amino and organic acid‐related inborn errors of metabolism: An overview on European data
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Inherited Metabolic Disease"
DOI: 10.1002/jimd.12318
Abstract: This study provides a general overview on liver and/or kidney transplantation in patients with an amino and organic acid‐related disorder (AOA) with the aim to investigate patient characteristics and global outcome in Europe. This study… read more here.
Keywords: liver kidney; kidney transplantation; amino organic; organic acid ... See more keywords
Primary hyperoxaluria: Long-term outcomes of isolated kidney versus simultaneous liver/kidney transplant.
Sign Up to like & getrecommendations! Published in 2024 at "Journal of pediatric gastroenterology and nutrition"
DOI: 10.1002/jpn3.12315
Abstract: OBJECTIVES To compare long-term transplant outcomes (organ rejection and retransplant) of simultaneous liver/kidney transplant (SLK) versus isolated kidney transplant (IK) for patients with primary hyperoxaluria (PH). METHODS The Rare Kidney Stone Consortium PH registry was… read more here.
Keywords: long term; transplant; patients underwent; kidney transplant ... See more keywords
Marginal quality kidneys for simultaneous liver‐kidney transplantation: To pass or double down?
Sign Up to like & getrecommendations! Published in 2017 at "Liver Transplantation"
DOI: 10.1002/lt.24669
Abstract: Renal dysfunction is common in patients awaiting a liver transplant, and although often potentially reversible, simultaneous liver-kidney transplantation (SLKT) is indicated in some recipients. Since adoption of Model for End-Stage Liver Disease (MELD) score allocation… read more here.
Keywords: liver kidney; quality; kidney transplantation; transplantation ... See more keywords
Longterm renal allograft survival after sequential liver‐kidney transplantation from a single living donor
Sign Up to like & getrecommendations! Published in 2017 at "Liver Transplantation"
DOI: 10.1002/lt.24676
Abstract: Combined liver‐kidney transplantation (CLKT) is well established as a definitive therapy with the potential to provide complete recovery for certain liver‐kidney diseases, although the results might be contingent on the cause of transplantation. The purposes… read more here.
Keywords: liver kidney; survival; transplantation; single living ... See more keywords
The role of the kidney in combined liver‐kidney transplantation
Sign Up to like & getrecommendations! Published in 2018 at "Liver Transplantation"
DOI: 10.1002/lt.24995
Abstract: In this issue of Liver Transplantation, Ekser et al. report the outcomes of combined liver-kidney transplantation (CLKT) recipients who had delayed implantation, a mean of 50 hours, of the kidney. This approach to dual organ… read more here.
Keywords: liver kidney; kidney transplantation; transplantation; combined liver ... See more keywords
Kidney Graft Outcomes in High Immunological Risk Simultaneous Liver‐Kidney Transplants
Sign Up to like & getrecommendations! Published in 2020 at "Liver Transplantation"
DOI: 10.1002/lt.25726
Abstract: Recipients of simultaneous liver‐kidney transplantations (SLKTs) have a lower risk of rejection compared with recipients of kidney transplants alone. However, there is disagreement about the impact of pretransplant anti–human leukocyte antigen sensitization on patient and… read more here.
Keywords: liver kidney; risk; graft; group ... See more keywords
Burden of early hospitalization after simultaneous liver–kidney transplantation: Results from the US Multicenter SLKT Consortium
Sign Up to like & getrecommendations! Published in 2022 at "Liver Transplantation"
DOI: 10.1002/lt.26523
Abstract: The burden of early hospitalization (within 6 months) following simultaneous liver–kidney transplant (SLKT) is not known. We examined risk factors associated with early hospitalization after SLKT and their impact on patient mortality conditional on 6‐month… read more here.
Keywords: simultaneous liver; burden early; early hospitalization; hospitalization ... See more keywords
The p53/p21/p16 and PI3K/Akt signaling pathways are involved in the ameliorative effects of maltol on D‐galactose‐induced liver and kidney aging and injury
Sign Up to like & getrecommendations! Published in 2021 at "Phytotherapy Research"
DOI: 10.1002/ptr.7142
Abstract: Successive evidence has established that maltol, a flavor‐enhancing agent, could provide resistance to oxidative stress‐induced tissue injury in various animal models though its benefits for aging‐induced liver and kidney injuries are still undetermined. In the… read more here.
Keywords: liver kidney; p53 p21; induced liver; p21 p16 ... See more keywords
Curcumin functions as an anti‐inflammatory and antioxidant agent on arsenic‐induced hepatic and kidney injury by inhibiting MAPKs/NF‐κB and activating Nrf2 pathways
Sign Up to like & getrecommendations! Published in 2021 at "Environmental Toxicology"
DOI: 10.1002/tox.23330
Abstract: Chronic arsenic exposure has been associated with various toxic effects, especially to the organs of liver and kidney. As a plant polyphenol, curcumin is the most vital bioactive ingredient of turmeric and has a wide… read more here.
Keywords: anti inflammatory; liver kidney; inflammatory antioxidant; arsenic induced ... See more keywords