Laparoscopic vs Open Surgery for Colorectal Liver Metastases
Sign Up to like & getrecommendations! Published in 2018 at "JAMA Surgery"
DOI: 10.1001/jamasurg.2018.2107
Abstract: Importance Surgery represents the mainstay treatment of colorectal liver metastases. Indications for the laparoscopic approach in this setting have been widened and there is a need to confirm the benefits of minimally invasive liver surgery… read more here.
Keywords: surgery; colorectal liver; approach; liver metastases ... See more keywords
Prognostic impact of perihepatic lymph node metastases in patients with resectable colorectal liver metastases
Sign Up to like & getrecommendations! Published in 2018 at "British Journal of Surgery"
DOI: 10.1002/bjs.10822
Abstract: Although perihepatic lymph node metastases (PLNMs) are known to be a poor prognosticator for patients with colorectal liver metastases (CRLMs), optimal management remains unclear. This study aimed to determine the risk factors for PLNMs, and… read more here.
Keywords: patients resectable; colorectal liver; perihepatic lymph; liver metastases ... See more keywords
Biomarkers in colorectal liver metastases
Sign Up to like & getrecommendations! Published in 2018 at "British Journal of Surgery"
DOI: 10.1002/bjs.10834
Abstract: Despite a 5‐year overall survival rate of 58 per cent after liver resection for colorectal liver metastases (CLMs), more than half of patients develop recurrence, highlighting the need for accurate risk stratification and prognostication. Traditional… read more here.
Keywords: liver metastases; biomarkers colorectal; colorectal liver; liver ... See more keywords
Effects of somatic alterations at pathway level are more mechanism‐explanatory and clinically applicable to quantity of liver metastases of colorectal cancer
Sign Up to like & getrecommendations! Published in 2019 at "Cancer Medicine"
DOI: 10.1002/cam4.2368
Abstract: The quantity of metastases lesions is an important reference when it comes to making a more informed treatment decision for patients with colorectal cancer liver metastases. However, the molecular alterations in patients with different numbers… read more here.
Keywords: effects somatic; liver metastases; colorectal cancer; quantity ... See more keywords
Circulating tumor DNA for prognosis assessment and postoperative management after curative‐intent resection of colorectal liver metastases
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Cancer"
DOI: 10.1002/ijc.33924
Abstract: The recurrence rate of colorectal liver metastases (CRLM) patients treated with curative intent is above 50%. Standard of care surveillance includes intensive computed tomographic (CT) imaging as well as carcinoembryonic antigen (CEA) measurements. Nonetheless, relapse… read more here.
Keywords: liver metastases; curative intent; ctdna status; colorectal liver ... See more keywords
Host phenotype is associated with reduced survival independent of tumour biology in patients with colorectal liver metastases
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cachexia, Sarcopenia and Muscle"
DOI: 10.1002/jcsm.12358
Abstract: Most prognostic scoring systems for colorectal liver metastases (CRLMs) account for factors related to tumour biology. Little is known about the effects of the host phenotype to the tumour. Our objective was to delineate the… read more here.
Keywords: tumour biology; colorectal liver; host phenotype; biology ... See more keywords
Impact of RAS mutations on the immune infiltrate of colorectal liver metastases: A preliminary study
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Leukocyte Biology"
DOI: 10.1002/jlb.5ab0220-608r
Abstract: Kirsten rat sarcoma viral oncogene homolog KRAS proto‐oncogene is the most common altered gene in colorectal cancer (CRC). Determining its mutational status, which is associated with worse prognosis and resistance to anti‐epidermal growth factor receptor… read more here.
Keywords: liver metastases; kras mutated; ras mutations; study ... See more keywords
Abbreviated Gadoxetic Acid‐Enhanced MRI for the Detection of Liver Metastases in Patients With Potentially Resectable Pancreatic Ductal Adenocarcinoma
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Magnetic Resonance Imaging"
DOI: 10.1002/jmri.28059
Abstract: Gadoxetic acid‐enhanced magnetic resonance imaging (MRI) is useful in detecting liver metastases from pancreatic ductal adenocarcinoma (PDAC). However, the long examination time limits its utility in the initial workup of patients with PDAC. read more here.
Keywords: pancreatic ductal; ductal adenocarcinoma; gadoxetic acid; liver metastases ... See more keywords
Influence of neoadjuvant chemotherapy on resection of primary colorectal liver metastases: A propensity score analysis
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Surgical Oncology"
DOI: 10.1002/jso.24631
Abstract: There is ongoing debate about whether patients planned for liver resection of colorectal liver metastases (CRLM) benefit from neoadjuvant chemotherapy (NC). Therefore, we performed a retrospective survival analysis of patients with and without NC prior… read more here.
Keywords: liver metastases; resection; neoadjuvant chemotherapy; colorectal liver ... See more keywords
Liver transplantation for unresectable colorectal liver metastases: A systematic review
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Surgical Oncology"
DOI: 10.1002/jso.24671
Abstract: The use of liver transplantation (LT) for liver metastases attempted in the early 1990's was associated with poor perioperative outcomes and unacceptably low overall survival. Recently, there has been renewed interest in LT as a… read more here.
Keywords: systematic review; colorectal liver; liver; liver transplantation ... See more keywords
The prognosis of colorectal cancer liver metastases associated with inflammatory bowel disease: An exploratory analysis
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Surgical Oncology"
DOI: 10.1002/jso.25251
Abstract: In contrast with sporadic colorectal cancer liver metastases (CRLM), inflammatory bowel disease (IBD)‐related CRLM have not been studied to date. read more here.
Keywords: bowel disease; inflammatory bowel; colorectal cancer; cancer liver ... See more keywords