Development of Halofluorochromic Polymer Nanoassemblies for the Potential Detection of Liver Metastatic Colorectal Cancer Tumors Using Experimental and Computational Approaches
Sign Up to like & getrecommendations! Published in 2017 at "Pharmaceutical Research"
DOI: 10.1007/s11095-017-2245-9
Abstract: PurposeTo develop polymer nanoassemblies (PNAs) modified with halofluorochromic dyes to allow for the detection of liver metastatic colorectal cancer (CRC) to improve therapeutic outcomes.MethodsWe combine experimental and computational approaches to evaluate macroscopic and microscopic PNA… read more here.
Keywords: metastatic colorectal; liver metastatic; detection liver; polymer nanoassemblies ... See more keywords
An astonishing case of liver-only metastatic colorectal cancer cured by FOLFOXIRI alone.
Sign Up to like & getrecommendations! Published in 2019 at "Anti-Cancer Drugs"
DOI: 10.1097/cad.0000000000000761
Abstract: The array of tools currently available and the aim of treatment make choosing the best therapeutic strategy in metastatic colorectal cancer (CRC) an increasing challenge worldwide. We present the case of a 53-year-old man with… read more here.
Keywords: liver metastatic; case; cancer; metastatic colorectal ... See more keywords
Prediction of the differences in tumor mutation burden between primary and metastatic lesions by radiogenomics.
Sign Up to like & getrecommendations! Published in 2021 at "Cancer science"
DOI: 10.1111/cas.15173
Abstract: Tumor mutational burden (TMB) is gaining attention as a biomarker for responses to immune checkpoint inhibitors in cancer patients. In this study, we evaluated the status of TMB in primary and liver metastatic lesions in… read more here.
Keywords: liver metastatic; metastatic lesions; primary liver; tmb ... See more keywords
Curable response to crizotinib in a patient with liver metastatic inflammatory myofibroblastic tumour carrying a TFG‐ROS1 fusion
Sign Up to like & getrecommendations! Published in 2022 at "Liver International"
DOI: 10.1111/liv.15456
Abstract: An 8- year- old girl presented with a 2- month history of jaundice. The physical examination revealed yellowing of the skin and sclera. Liver function tests revealed elevated direct bilirubin (103 μ mol/L), alkaline phosphatase… read more here.
Keywords: crizotinib patient; response crizotinib; metastatic inflammatory; curable response ... See more keywords
Abstract 3513: Developing a 3D biomimetic liver metastatic niche model for pancreatic cancer
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Research"
DOI: 10.1158/1538-7445.am2023-3513
Abstract: Pancreatic ductal adenocarcinoma (PDAC) is the 3rd leading cause of cancer death in the Unites States with a 5-year survival rate of only 11%. Early diagnosis is very difficult and thus 53% of patients are… read more here.
Keywords: liver metastatic; metastatic niche; cancer; model ... See more keywords
Resection of primary tumor in liver only metastatic midgut neuroendocrine tumors.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2019.37.4_suppl.446
Abstract: 446 Background: Surgical management of metastatic midgut neuroendocrine tumors (NET) remains controversial. Resection of primary tumor only without liver resection is advocated only in select patients, frequently for palliation. Additionally, no standard algorithm exists, and… read more here.
Keywords: primary tumor; liver metastatic; metastatic midgut; resection ... See more keywords
A phase Ib study of pembrolizumab (Pem) in combination with stereotactic body radiotherapy (SBRT) for resectable liver metastatic colorectal cancer (CRC).
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2019.37.4_suppl.680
Abstract: 680 Background: Adjunctive therapies are essential to enhance the effect of anti-PD1 therapies for the treatment of microsatellite stable (MSS) colorectal cancer. SBRT is utilized to treat liver metastatic CRC, causing an increase in immunogenic… read more here.
Keywords: pem; combination; sbrt; liver metastatic ... See more keywords
Clinical significance and changes to the immune microenvironment of colorectal cancer patients with liver metastasis
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Gastrointestinal Oncology"
DOI: 10.21037/jgo-22-1169
Abstract: Background Liver metastasis is common in colorectal cancer patients. Immunotherapy covers a wide range of tumor types and is safer than traditional radiotherapy and chemotherapy. However, its overall effective rate is only 20–40%. At present,… read more here.
Keywords: cancer patients; colorectal cancer; liver metastasis; patients liver ... See more keywords
Liver Metastatic Breast Cancer: Epidemiology, Dietary Interventions, and Related Metabolism
Sign Up to like & getrecommendations! Published in 2022 at "Nutrients"
DOI: 10.3390/nu14122376
Abstract: The median overall survival of patients with metastatic breast cancer is only 2–3 years, and for patients with untreated liver metastasis, it is as short as 4–8 months. Improving the survival of women with breast… read more here.
Keywords: cancer; breast cancer; metastatic breast; liver metastatic ... See more keywords