Protective effects of lycopene on TiO2 nanoparticle‐induced damage in the liver of mice
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Applied Toxicology"
DOI: 10.1002/jat.4433
Abstract: Titanium dioxide nanoparticles (nano‐TiO2) is one of the most widely used and produced nanomaterials. Studies have demonstrated that nano‐TiO2 could induce hepatotoxicity through oxidative stress, and lycopene has strong antioxidant capacity. The present study aimed… read more here.
Keywords: damage; tio2; lycopene; liver mice ... See more keywords
Dietary β-conglycinin prevents acute ethanol-induced fatty liver in mice.
Sign Up to like & getrecommendations! Published in 2017 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2017.08.155
Abstract: Alcoholic fatty liver is the earliest stage of alcohol-induced liver disease leading to liver cirrhosis. β-Conglycinin, one of the soy proteins, is known to prevent non-alcoholic fatty liver, hyperlipidemia and obesity. Therefore, we examined whether… read more here.
Keywords: fatty liver; conglycinin; ethanol; mice ... See more keywords
Metabolomics study on liver of db/db mice treated with curcumin using UPLC-Q-TOF-MS.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of pharmaceutical and biomedical analysis"
DOI: 10.1016/j.jpba.2022.114771
Abstract: A metabolomics method based on ultra-performance liquid chromatography quadrupole time-of-flight mass spectrometry (UPLC-Q-TOF-MS) was applied to study the metabolic changes of liver in db/db mice administered with curcumin. After one week of acclimating to feeding,… read more here.
Keywords: treatment group; uplc tof; treatment; liver mice ... See more keywords
Metabolic profiles of pomalidomide in human plasma simulated with pharmacokinetic data in control and humanized-liver mice
Sign Up to like & getrecommendations! Published in 2017 at "Xenobiotica"
DOI: 10.1080/00498254.2016.1247218
Abstract: Abstract 1. Pomalidomide has been shown to be potentially teratogenic in thalidomide-sensitive animal species such as rabbits. Screening for thalidomide analogs devoid of teratogenicity/toxicity – attributable to metabolites formed by cytochrome P450 enzymes – but having… read more here.
Keywords: profiles pomalidomide; human plasma; liver mice; humanized liver ... See more keywords
Fluorescence Detection of Cell Death in Liver of Mice Treated with Thioacetamide
Sign Up to like & getrecommendations! Published in 2018 at "Toxicological Research"
DOI: 10.5487/tr.2018.34.1.001
Abstract: The purpose of this study was to detect cell death in the liver of mice treated with thioacetamide (TAA) using fluorescence bioimaging and compare this outcome with that using conventional histopathological examination. At 6 weeks… read more here.
Keywords: liver mice; cell death; mice; fluorescence ... See more keywords