Physiological levels of formate activate mitochondrial superoxide/hydrogen peroxide release from mouse liver mitochondria
Sign Up to like & getrecommendations! Published in 2017 at "FEBS Letters"
DOI: 10.1002/1873-3468.12777
Abstract: Here, we found that formate, an essential one‐carbon metabolite, activates superoxide ( O2·− )/hydrogen peroxide (H2O2) release from mitochondria. Sodium formate (30 μm) induces a significant increase in O2·− /H2O2 production in liver mitochondria metabolizing… read more here.
Keywords: hydrogen peroxide; liver mitochondria; superoxide hydrogen; h2o2 ... See more keywords
Transmission electron microscopy of the liver mitochondria of N-Nitrosodibutylamine-treated mice.
Sign Up to like & getrecommendations! Published in 2021 at "Microscopy research and technique"
DOI: 10.1002/jemt.23842
Abstract: N-Nitrosodibutylamine (DBN) has been found in a wide variety of products because of the nitrosation of amines present in these products. An extensive series of synthesis and carcinogenicity studies of various compounds related to DBN… read more here.
Keywords: microscopy; liver mitochondria; treated mice; electron microscopy ... See more keywords
Effect of hypothermia on the functional activity of liver mitochondria of grass snake (Natrix natrix): inhibition of succinate-fueled respiration and K+ transport, ROS-induced activation of mitochondrial permeability transition
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Bioenergetics and Biomembranes"
DOI: 10.1007/s10863-019-09796-6
Abstract: The article considers the comparative analysis of the functional activity of mitochondria isolated from the liver of grass snakes, Natrix natrix (Linnaeus, 1758) that were kept at different temperatures (23–26 °C and 4-5 °C). It was found… read more here.
Keywords: grass; liver mitochondria; inhibition; respiration ... See more keywords
Itaconic acid impairs the mitochondrial function by the inhibition of complexes II and IV and induction of the permeability transition pore opening in rat liver mitochondria.
Sign Up to like & getrecommendations! Published in 2020 at "Biochimie"
DOI: 10.1016/j.biochi.2020.07.011
Abstract: Itaconic acid (methylene-succinic acid, ItA) is an unsaturated dicarboxylic acid that is secreted by mammalian macrophages in response to a pro-inflammatory stimulus and shows an anti-inflammatory/antibacterial effect. Being a mitochondrial metabolite, it exhibits an inhibitory… read more here.
Keywords: liver mitochondria; effect; itaconic acid; rat liver ... See more keywords
Energy metabolism and oxidative status of rat liver mitochondria in conditions of experimentally induced hyperthyroidism.
Sign Up to like & getrecommendations! Published in 2020 at "Mitochondrion"
DOI: 10.1016/j.mito.2020.04.005
Abstract: The aim of the present work was to investigate the energy metabolism and antioxidant status of rat liver mitochondria using a model of hyperthyroidism. In experimental animals, the level of triiodothyronine and thyroxine was increased… read more here.
Keywords: liver mitochondria; hyperthyroidism; status rat; energy metabolism ... See more keywords
The role of RIPK3 in liver mitochondria bioenergetics and function.
Sign Up to like & getrecommendations! Published in 2021 at "European journal of clinical investigation"
DOI: 10.1111/eci.13648
Abstract: Receptor interacting protein kinase 3 (RIPK3) is a key player of regulated necrosis or necroptosis, an inflammatory form of cell death possibly governing outcomes in chronic liver diseases, such as non-alcoholic fatty liver disease and… read more here.
Keywords: liver mitochondria; ripk3; role ripk3; ripk3 liver ... See more keywords
Proteomic analysis of liver mitochondria of db/db mice treated with grape seed procyanidin B2.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of food biochemistry"
DOI: 10.1111/jfbc.13443
Abstract: Hepatic damage has been recognized as one of the major complications in diabetes mellitus. Our previous studies have verified that grape seed procyanidin B2 (GSPB2) played a protective effect on hepatic damage of diabetes. We… read more here.
Keywords: seed; liver mitochondria; seed procyanidin; damage ... See more keywords
Protective effect of metformin on toxicity of butyric acid and arsenic in isolated liver mitochondria and langerhans islets in male mice: an in vitro study
Sign Up to like & getrecommendations! Published in 2017 at "Iranian Journal of Basic Medical Sciences"
DOI: 10.22038/ijbms.2017.9567
Abstract: Objective(s): Arsenic, a toxic metal in drinking water and butyric acid (BA) is a free fatty acid found in many foods. These two can induce oxidative stress in some tissues. The present study investigated the… read more here.
Keywords: protective effect; liver mitochondria; insulin secretion; metformin ... See more keywords
Age-Dependent Changes in the Function of Mitochondrial Membrane Permeability Transition Pore in Rat Liver Mitochondria.
Sign Up to like & getrecommendations! Published in 2021 at "Physiological research"
DOI: 10.33549//physiolres.934734
Abstract: Mitochondria play an important role in the cell aging process. Changes in calcium homeostasis and/or increased reactive oxygen species (ROS) production lead to the opening of mitochondrial permeability transition pore (MPTP), depolarization of the inner… read more here.
Keywords: age; transition pore; rat liver; permeability transition ... See more keywords
Decline in Liver Mitochondria Metabolic Function Is Restored by Hochuekkito Through Sirtuin 1 in Aged Mice With Malnutrition
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Physiology"
DOI: 10.3389/fphys.2022.848960
Abstract: Malnutrition impairs basic daily activities and leads to physical frailty, which is aggravated in the elderly compared with young adults. It is also well-known that the elderly are more vulnerable to metabolic stress. Therefore, in… read more here.
Keywords: locomotor activity; function; metabolic function; liver mitochondria ... See more keywords
Rosemary (Rosmarinus officinalis L.) Glycolic Extract Protects Liver Mitochondria from Oxidative Damage and Prevents Acetaminophen-Induced Hepatotoxicity
Sign Up to like & getrecommendations! Published in 2023 at "Antioxidants"
DOI: 10.3390/antiox12030628
Abstract: Rosmarinus officinalis L. (rosemary) is an aromatic culinary herb. Native to the Mediterranean region, it is currently cultivated worldwide. In addition to its use as a condiment in food preparation and in teas, rosemary has… read more here.
Keywords: liver mitochondria; damage; glycolic extract; rosmarinus officinalis ... See more keywords