Fluorescing fatty acids in rat fatty liver models.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of biophotonics"
DOI: 10.1002/jbio.201600195
Abstract: The autofluorescence (AF) of NAD(P)H and flavins has been at the basis of many in-situ studies of liver energy metabolism and functionality. Conversely, few data have been so far reported on fluorescing lipids. In this… read more here.
Keywords: liver models; fatty liver; lipid extracts; fatty acids ... See more keywords
In Vitro Three-Dimensional Liver Models for Nanomaterial DNA Damage Assessment.
Sign Up to like & getrecommendations! Published in 2021 at "Small"
DOI: 10.1002/smll.202006055
Abstract: Whilst the liver possesses the ability to repair and restore sections of damaged tissue following acute injury, prolonged exposure to engineered nanomaterials (ENM) may induce repetitive injury leading to chronic liver disease. Screening ENM cytotoxicity… read more here.
Keywords: dna damage; liver models; liver; assessment ... See more keywords
IL-6–GP130 signaling protects human hepatocytes against lipid droplet accumulation in humanized liver models
Sign Up to like & getrecommendations! Published in 2023 at "Science Advances"
DOI: 10.1126/sciadv.adf4490
Abstract: Liver steatosis is an increasing health issue with few therapeutic options, partly because of a paucity of experimental models. In humanized liver rodent models, abnormal lipid accumulation in transplanted human hepatocytes occurs spontaneously. Here, we… read more here.
Keywords: human hepatocytes; accumulation; humanized liver; gp130 signaling ... See more keywords
Functional Evaluation of 3D Liver Models Labeled with Polysaccharide Functionalized Magnetic Nanoparticles
Sign Up to like & getrecommendations! Published in 2022 at "Materials"
DOI: 10.3390/ma15217823
Abstract: Establishing a rapid in vitro evaluation system for drug screening is essential for the development of new drugs. To reproduce tissues/organs with functions closer to living organisms, in vitro three-dimensional (3D) culture evaluation using microfabrication… read more here.
Keywords: liver; various nanoparticles; functional evaluation; evaluation liver ... See more keywords