Effect of a neural relay on liver regeneration in mice: activation of serotonin release from the gastrointestinal tract
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DOI: 10.1002/2211-5463.12382
Abstract: The development of therapeutic options to promote hepatic regeneration following severe liver injury is essential. While humoral factors have been reported as mechanisms of liver regeneration, the contributions of interorgan communication to liver regeneration have… read more here.
Keywords: serotonin release; liver regeneration; regeneration; activation serotonin ... See more keywords
Advanced Biomaterials and Processing Methods for Liver Regeneration: State-of-the-Art and Future Trends.
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DOI: 10.1002/adhm.201901435
Abstract: Liver diseases contribute markedly to the global burden of mortality and disease. The limited organ disposal for orthotopic liver transplantation results in a continuing need for alternative strategies. Over the past years, important progress has… read more here.
Keywords: biomaterials processing; future trends; liver regeneration; methods liver ... See more keywords
Interleukin 6–dependent genomic instability heralds accelerated carcinogenesis following liver regeneration on a background of chronic hepatitis
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DOI: 10.1002/hep.29004
Abstract: Liver cancer, which typically develops on a background of chronic liver inflammation, is now the second leading cause of cancer mortality worldwide. For patients with liver cancer, surgical resection is a principal treatment modality that… read more here.
Keywords: background chronic; liver regeneration; genomic instability; hepatology ... See more keywords
Intrahepatic T‐Cell Receptor β Immune Repertoire Is Essential for Liver Regeneration
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DOI: 10.1002/hep.30067
Abstract: T lymphocytes synergize with the cellular immune system to promote hepatocyte regeneration. The T‐cell receptor (TCR) immune repertoire is closely associated with the host immune response and regenerative proliferation. High‐throughput sequencing of TCR provides deep… read more here.
Keywords: immune repertoire; liver regeneration; regeneration; cell receptor ... See more keywords
Liver‐Selective MMP‐9 Inhibition in the Rat Eliminates Ischemia‐Reperfusion Injury and Accelerates Liver Regeneration
Sign Up to like & getrecommendations! Published in 2019 at "Hepatology"
DOI: 10.1002/hep.30169
Abstract: Recruitment of liver sinusoidal endothelial cell progenitor cells (sprocs) from the bone marrow by vascular endothelial growth factor‐stromal cell‐derived factor‐1 (VEGF‐sdf‐1) signaling promotes recovery from injury and drives liver regeneration. Matrix metalloproteinases (MMPs) can proteolytically… read more here.
Keywords: selective mmp; liver regeneration; liver selective; mmp inhibition ... See more keywords
Response to: Characterization of CD169+ macrophages in liver regeneration: tissue distribution and fate?
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DOI: 10.1002/hep.30600
Abstract: It is with great appreciation that we read the comment from Ait Ahmed et al., who raise questions which are equally interesting and important (1). In our manuscript we identify an important role of B cells… read more here.
Keywords: liver regeneration; regeneration; macrophages liver; response characterization ... See more keywords
Letter to the Editor: Characterization of CD169+ Macrophages in Liver Regeneration: Tissue Distribution and Fate?
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DOI: 10.1002/hep.30601
Abstract: We read this article by Behnke et al. recently published in Hepatology with great interest.(1) This study demonstrated the role of B cells in favoring liver regeneration, notably by maintaining splenic CD169+ macrophages and hepatic IL-6… read more here.
Keywords: cd169 macrophages; liver regeneration; letter editor; hepatology ... See more keywords
Mammalian Target of Rapamycin Complex 1 Signaling Is Required for the Dedifferentiation From Biliary Cell to Bipotential Progenitor Cell in Zebrafish Liver Regeneration
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DOI: 10.1002/hep.30790
Abstract: The liver has a high regenerative capacity. Upon two‐thirds partial hepatectomy, the hepatocytes proliferate and contribute to liver regeneration. After severe liver injury, when the proliferation of residual hepatocytes is blocked, the biliary epithelial cells… read more here.
Keywords: liver regeneration; dedifferentiation; cell; proliferation ... See more keywords
Annexin A6 Is Critical to Maintain Glucose Homeostasis and Survival During Liver Regeneration in Mice
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DOI: 10.1002/hep.31232
Abstract: Liver regeneration requires the organized and sequential activation of events that lead to restoration of hepatic mass. During this process, other vital liver functions need to be preserved, such as maintenance of blood glucose homeostasis,… read more here.
Keywords: glucose homeostasis; liver regeneration; annexin critical; liver ... See more keywords
Farnesoid X Receptor Activation Impairs Liver Progenitor Cell–Mediated Liver Regeneration via the PTEN‐PI3K‐AKT‐mTOR Axis in Zebrafish
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DOI: 10.1002/hep.31679
Abstract: Following mild liver injury, pre‐existing hepatocytes replicate. However, if hepatocyte proliferation is compromised, such as in chronic liver diseases, biliary epithelial cells (BECs) contribute to hepatocytes through liver progenitor cells (LPCs), thereby restoring hepatic mass… read more here.
Keywords: receptor activation; liver regeneration; regeneration; liver progenitor ... See more keywords
CCL5 confines liver regeneration by downregulating reparative macrophage-derived HGF in an FoxO3a dependent manner.
Sign Up to like & getrecommendations! Published in 2022 at "Hepatology"
DOI: 10.1002/hep.32458
Abstract: BACKGROUND AND AIMS Liver regeneration is vital for the recovery of liver function after hepatectomy. Limited regeneration capacity together with insufficient remnant liver volume is a risk factor for post-hepatectomy liver failure resulting from small-for-size… read more here.
Keywords: liver regeneration; hepatectomy; phx; ccl5 ... See more keywords