Single-cell RNA sequencing reveals the heterogeneity of liver-resident immune cells in human
Sign Up to like & getrecommendations! Published in 2020 at "Cell Discovery"
DOI: 10.1038/s41421-020-0157-z
Abstract: The liver plays a critical role in both immune defense and tolerance in the body. The liver-resident immune cells (LrICs) determine the immune properties, but the unique composition and heterogeneity of these cells are incompletely… read more here.
Keywords: immune; heterogeneity; resident immune; liver resident ... See more keywords
Liver-Derived TGF-β Maintains the EomeshiTbetlo Phenotype of Liver Resident Natural Killer Cells
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2019.01502
Abstract: The adult human liver hosts a complex repertoire of liver resident and transient natural killer (NK) cell populations with diverse phenotypes and functions. Liver resident NK cells are CD56bright NK cells defined by a unique… read more here.
Keywords: resident cells; phenotype liver; liver resident; liver ... See more keywords
The Immunological Effect of Oxygen Carriers on Normothermic Ex Vivo Liver Perfusion
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.833243
Abstract: Introduction Normothermic ex vivo liver perfusion (NEVLP) is an organ preservation method that allows liver graft functional assessment prior to transplantation. One key component of normothermic perfusion solution is an oxygen carrier to provide oxygen… read more here.
Keywords: oxygen carriers; liver; liver resident; oxygen ... See more keywords
The imbalance of liver resident macrophages polarization promotes chronic autoimmune hepatitis development in mice
Sign Up to like & getrecommendations! Published in 2023 at "PeerJ"
DOI: 10.7717/peerj.14871
Abstract: Background Autoimmune hepatitis (AIH) is a chronic immune-mediated inflammatory liver disease. At present, it is largely unknown how the innate immune cells influence AIH development. Objective To inquiry about mechanism of liver resident macrophages in… read more here.
Keywords: development; macrophages polarization; resident macrophages; liver resident ... See more keywords