Variation in diagnostic NAFLD/NASH read-outs in paired liver samples from rodent models.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of pharmacological and toxicological methods"
DOI: 10.1016/j.vascn.2019.106651
Abstract: INTRODUCTION In animal models of non-alcoholic fatty liver disease (NAFLD), assessment of disease severity and treatment effects of drugs rely on histopathological scoring of liver biopsies. However, little is known about the sampling variation in… read more here.
Keywords: variation; paired liver; liver; rodent models ... See more keywords
A sensitive and group-specific monoclonal antibody-based indirect competitive ELISA for the determination of salbutamol in swine meat and liver samples
Sign Up to like & getrecommendations! Published in 2017 at "Analytical Methods"
DOI: 10.1039/c7ay01628j
Abstract: The use of salbutamol (SAL), a β-adrenergic receptor agonist (β-agonist) that could enhance the lean meat-to-fat ratio in livestock, has been prohibited as an additive in animal feeds for livestock production in many countries due… read more here.
Keywords: swine meat; sal; meat liver; group ... See more keywords
Ultrasensitive immunochromatographic strips for fast screening of the nicarbazin marker in chicken breast and liver samples based on monoclonal antibodies
Sign Up to like & getrecommendations! Published in 2020 at "Analytical Methods"
DOI: 10.1039/d0ay00414f
Abstract: Nicarbazin is an anticoccidial drug with a residue limit in animal husbandry. 4,4′-Dinitrocarbanilide (DNC) is the residue marker of nicarbazin. In this research, designed and based on new haptens, a sensitive and specific monoclonal antibody… read more here.
Keywords: breast liver; marker; chicken breast; liver samples ... See more keywords
Comparison of magnetic bead and rapid swab RNA extraction methods for detecting rabbit hemorrhagic disease virus 2 in rabbit liver samples.
Sign Up to like & getrecommendations! Published in 2023 at "BioTechniques"
DOI: 10.2144/btn-2022-0022
Abstract: We compared a bead RNA extraction method with a one-tube method that required only a heat block and ice. RNA was first extracted from liver samples from nine rabbits dying from rabbit hemorrhagic disease virus… read more here.
Keywords: rna extraction; liver samples; extraction; rabbit hemorrhagic ... See more keywords
The Association Between Promoter Tandem Repeat Polymorphism (pVNTR) and CYP2C9 Gene Expression in Human Liver Samples
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DOI: 10.3390/genes16020213
Abstract: CYP2C9 metabolizes approximately 20% of clinically administered drugs. Several single-nucleotide polymorphisms (SNPs) of CYP2C9 (e.g., *2, *3, *8, and rs12777823) are used as biomarkers to predict CYP2C9 activity. However, a large proportion of variability in… read more here.
Keywords: cyp2c9 expression; pvntr; liver samples; human liver ... See more keywords
Association Between UGT1A1 mRNA Expression and Cis-Acting Genetic Variants and Trans-Acting Transcriptional Regulators in Human Liver Samples
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DOI: 10.3390/genes16080971
Abstract: Background: UDP-glucuronosyltransferase 1A1 (UGT1A1) metabolizes endogenous substances and pharmaceuticals. Genetic polymorphisms, particularly TA repeats in the UGT1A1 promoter TATA region (UGT1A1*28/*36/*37) and a nearby single-nucleotide polymorphism (SNP) rs887829, are associated with UGT1A1-related phenotypes and used… read more here.
Keywords: trans acting; ugt1a1 expression; liver samples; genetic variants ... See more keywords