Liver‐Selective MMP‐9 Inhibition in the Rat Eliminates Ischemia‐Reperfusion Injury and Accelerates Liver Regeneration
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DOI: 10.1002/hep.30169
Abstract: Recruitment of liver sinusoidal endothelial cell progenitor cells (sprocs) from the bone marrow by vascular endothelial growth factor‐stromal cell‐derived factor‐1 (VEGF‐sdf‐1) signaling promotes recovery from injury and drives liver regeneration. Matrix metalloproteinases (MMPs) can proteolytically… read more here.
Keywords: selective mmp; liver regeneration; liver selective; mmp inhibition ... See more keywords