Time-Resolved Quantification of Nanoparticle Uptake, Distribution, and Impact in Precision-Cut Liver Slices.
Sign Up to like & getrecommendations! Published in 2020 at "Small"
DOI: 10.1002/smll.201906523
Abstract: Much effort within the nanosafety field is currently focused on the use of advanced in vitro models to reduce the gap between in vitro and in vivo studies. Within this context, precision-cut tissue slices are… read more here.
Keywords: impact; precision cut; nanoparticle; tissue ... See more keywords
The use of liver slices from the Cape vulture (Gyps coprotheres) to better understand the role of liver toxicity of non-steroidal anti-inflammatory drugs (NSAIDs) in vultures.
Sign Up to like & getrecommendations! Published in 2018 at "Environmental toxicology and pharmacology"
DOI: 10.1016/j.etap.2018.07.001
Abstract: Diclofenac, a non-steroidal anti-inflammatory drug (NSAID) was responsible for the death of millions of vultures on the Asian subcontinent, following the consumption of diclofenac contaminated carcasses. The aim of this research was to establish if… read more here.
Keywords: liver; cape vulture; toxicity; liver slices ... See more keywords
Development of a Novel Ex-vivo 3D Model to Screen Amoebicidal Activity on Infected Tissue
Sign Up to like & getrecommendations! Published in 2019 at "Scientific Reports"
DOI: 10.1038/s41598-019-44899-5
Abstract: Amoebiasis is a parasitic disease that causes thousands of deaths every year, its adverse effects and resistance to conventional treatments have led to the search of new treatment options, as well as the development of… read more here.
Keywords: liver slices; novel vivo; model; development novel ... See more keywords
Predicting physiologically-relevant oxygen concentrations in precision-cut liver slices using mathematical modelling
Sign Up to like & getrecommendations! Published in 2022 at "PLOS ONE"
DOI: 10.1371/journal.pone.0275788
Abstract: Precision cut liver slices represent an encouraging ex vivo method to understand the pathogenesis of liver disease alongside drug induced liver injury. Despite being more physiologically relevant compared to in vitro models, precision cut liver… read more here.
Keywords: precision cut; liver slices; oxygen; cut liver ... See more keywords