Phosphorylation of Androgen Receptor by mTORC1 Promotes Liver Steatosis and Tumorigenesis.
Sign Up to like & getrecommendations! Published in 2021 at "Hepatology"
DOI: 10.1002/hep.32120
Abstract: Androgen receptor (AR) has been reported to play an important role in the development and progression of man's prostate cancer. Hepatocellular carcinoma (HCC) is also male-dominant, but the role of AR in HCC remains poorly… read more here.
Keywords: liver steatosis; phosphorylation; androgen receptor; hcc ... See more keywords
Noninvasive assessment of liver steatosis in deceased donors: A pilot study
Sign Up to like & getrecommendations! Published in 2018 at "Liver Transplantation"
DOI: 10.1002/lt.25002
Abstract: The growing imbalance between the need and the availability of liver donors has resulted in an increasing use of extended liver criteria donors, which are more likely to have hepatic steatosis (HS) with a risk… read more here.
Keywords: liver steatosis; pilot study; liver procurement; liver ... See more keywords
Etiology of Liver Steatosis Influences the Severity of Ischemia/Reperfusion Injury and Survival After Liver Transplantation in Rats
Sign Up to like & getrecommendations! Published in 2020 at "Liver Transplantation"
DOI: 10.1002/lt.25814
Abstract: Liver steatosis is a leading cause of graft disposal in liver transplantation, though the degree of steatosis is often the single factor determining acceptability of the graft. We investigated how the cause of liver steatosis… read more here.
Keywords: liver steatosis; etiology; liver; reperfusion ... See more keywords
Hepatic Steatosis in Lean Patients: Risk Factors and Impact on Mortality
Sign Up to like & getrecommendations! Published in 2019 at "Digestive Diseases and Sciences"
DOI: 10.1007/s10620-019-06000-y
Abstract: The prognostic impact of liver steatosis in obese patients is well established. Limited data on the risk factors for and impact of hepatic steatosis in lean patients are available. Assess risk factors for liver steatosis… read more here.
Keywords: lean patients; liver steatosis; hepatic steatosis; risk factors ... See more keywords
Thioredoxin-1 promotes macrophage reverse cholesterol transport and protects liver from steatosis.
Sign Up to like & getrecommendations! Published in 2019 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2019.06.109
Abstract: Atherosclerosis is characterized by the accumulation of excess cholesterol in plaques. Reverse cholesterol transport (RCT) plays a key role in the removal of cholesterol. In the present study, we examined the effect of thioredoxin-1 (Trx-1)… read more here.
Keywords: protects liver; liver steatosis; reverse cholesterol; cholesterol ... See more keywords
Oral gallic acid improve liver steatosis and metabolism modulating hepatic lipogenic markers in obese mice
Sign Up to like & getrecommendations! Published in 2020 at "Experimental Gerontology"
DOI: 10.1016/j.exger.2020.110881
Abstract: INTRODUCTION Gallic acid (GA) is a natural endogenous polyphenol found in a variety of fruits, vegetables and wines, with beneficial effects on the energetic homeostasis. AIM The present study aimed to investigate oral gallic acid… read more here.
Keywords: liver steatosis; oral gallic; markers obese; gallic acid ... See more keywords
Metabolic recovery of lipodystrophy, liver steatosis, and pancreatic β cell proliferation after the withdrawal of OSI-906
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-04304-5
Abstract: Growth factor signaling via insulin receptor (IR) and IGF-1 receptor (IGF1R) plays several important roles in the pathogenesis of metabolic syndrome and diabetes. OSI-906 (linsitinib), an anti-tumor drug, is an orally bioavailable dual inhibitor of… read more here.
Keywords: liver steatosis; recovery; osi 906; cell proliferation ... See more keywords
Hyperglycemia-stimulating diet induces liver steatosis in sheep
Sign Up to like & getrecommendations! Published in 2020 at "Scientific Reports"
DOI: 10.1038/s41598-020-68909-z
Abstract: Hepatic steatosis is strongly associated with chronic liver disease and systemic metabolic disorder. Adipose lipolysis is a recognized principal source of intrahepatic fat in various metabolic disorders, including non-alcoholic fatty liver disease. We hypothesized that,… read more here.
Keywords: liver steatosis; stimulating diet; diet induces; hyperglycemia stimulating ... See more keywords
Comprehensive analysis of the translatome reveals the relationship between the translational and transcriptional control in high fat diet-induced liver steatosis
Sign Up to like & getrecommendations! Published in 2020 at "RNA Biology"
DOI: 10.1080/15476286.2020.1827193
Abstract: ABSTRACT Translational regulation plays a critical role in gene expression. However, there are few genome-wide studies on translational regulation in non-alcoholic fatty liver disease (NAFLD), which is a severe non-communicable epidemic worldwide. In this study,… read more here.
Keywords: fat diet; liver steatosis; control; analysis ... See more keywords
Expanding Research on Cannabis-Based Medicines for Liver Steatosis: A Low-Risk High-Reward Way Out of the Present Deadlock?
Sign Up to like & getrecommendations! Published in 2022 at "Cannabis and cannabinoid research"
DOI: 10.1089/can.2022.0014
Abstract: Obesity and nonalcoholic fatty liver disease (NAFLD) constitute global and growing epidemics that result in therapeutic dead ends. There is an urgent need for new and accessible treatments to improve and widen both preventive and… read more here.
Keywords: research cannabis; liver steatosis; expanding research; research ... See more keywords
Multidimensional Impact of Mediterranean Diet on IBD Patients
Sign Up to like & getrecommendations! Published in 2020 at "Inflammatory Bowel Diseases"
DOI: 10.1093/ibd/izaa097
Abstract: Abstract Background & Aims Malnutrition with the accumulation of fat tissue and nonalcoholic fatty liver disease (NAFLD) are conditions associated with inflammatory bowel disease (IBD). Visceral fat and NAFLD-related liver dysfunction can both worsen intestinal… read more here.
Keywords: mediterranean diet; liver steatosis; ibd patients; disease ... See more keywords