A small molecule Hedgehog agonist HhAg1.5 mediated reprogramming breaks the quiescence of noninjured liver stem cells for rescuing liver failure
Sign Up to like & getrecommendations! Published in 2019 at "Translational Research"
DOI: 10.1016/j.trsl.2018.10.004
Abstract: &NA; Liver is the second most transplanted organ according to United network for organ sharing. Due to shortage of compatible donors, surgical difficulties, immunological hindrance, and high postoperative cost, stem cell therapy is an attractive… read more here.
Keywords: hedgehog agonist; agonist hhag1; stem; stem cells ... See more keywords
Human Liver Stem Cell Derived Extracellular Vesicles Alleviate Kidney Fibrosis by Interfering with the β-Catenin Pathway through miR29b
Sign Up to like & getrecommendations! Published in 2021 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms221910780
Abstract: Human liver stem-cell-derived extracellular vesicles (HLSC-EVs) exhibit therapeutic properties in various pre-clinical models of kidney injury. We previously reported an overall improvement in kidney function following treatment with HLSC-EVs in a model of aristolochic acid… read more here.
Keywords: hlsc evs; catenin; stem cell; mir29b ... See more keywords