Abnormal Liver Tests in COVID‐19: A Retrospective Observational Cohort Study of 1,827 Patients in a Major U.S. Hospital Network
Sign Up to like & getrecommendations! Published in 2020 at "Hepatology"
DOI: 10.1002/hep.31487
Abstract: The coronavirus‐19 disease (COVID‐19) pandemic, caused by the severe acute respiratory syndrome coronavirus 2 virus, is associated with significant morbidity and mortality attributable to pneumonia, acute respiratory distress syndrome, and multiorgan failure. Liver injury has… read more here.
Keywords: retrospective observational; abnormal liver; tests covid; liver ... See more keywords
Emerging Tools to Support DILI Assessment in Clinical Trials with Abnormal Baseline Serum Liver Tests or Pre-existing Liver Diseases
Sign Up to like & getrecommendations! Published in 2025 at "Drug Safety"
DOI: 10.1007/s40264-024-01511-8
Abstract: Based on the late Dr. Hyman Zimmerman’s observation that hepatocellular drug-induced liver injury (DILI) leading to jaundice carries a ≥ 10% fatality risk (coined as Hy’s law by others), evaluation of Drug-Induced Serious Hepatotoxicity (eDISH)… read more here.
Keywords: baseline serum; liver tests; drug; dili ... See more keywords
Liver injury in patients with COVID-19 in comparison to patients with the pandemic influenza A (H1N1) 2009: a population-based study.
Sign Up to like & getrecommendations! Published in 2023 at "Scandinavian journal of gastroenterology"
DOI: 10.1080/00365521.2023.2204987
Abstract: BACKGROUND Elevated liver tests in patients with COVID-19 are widely reported. Population-based studies utilizing a validated analysis of drug-induced liver injury (DILI), with a control group of other viral illnesses and follow-up are largely lacking.… read more here.
Keywords: influenza h1n1; population based; elevated liver; liver tests ... See more keywords
Liver tests abnormalities with licensed antiviral drugs for COVID-19: a narrative review
Sign Up to like & getrecommendations! Published in 2022 at "Expert Opinion on Drug Safety"
DOI: 10.1080/14740338.2022.2160446
Abstract: ABSTRACT Introduction Liver involvement in COVID-19 is multifactorial, and the three potential mechanisms are direct hepatocyte viral damage, vascular or cellular damage during the cytokine storm of severe COVID-19 and drug-induced liver injury. To date,… read more here.
Keywords: narrative review; safety; liver; safety profile ... See more keywords
Persistently altered liver test results in hepatitis C patients after sustained virological response with direct‐acting antivirals
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DOI: 10.1111/jvh.12883
Abstract: Guidelines recommend evaluating persistent alteration of liver tests in HCV‐infected patients after sustained virological response (SVR) and its influence on liver disease progression. We studied the prevalence, etiology, associated factors and evolutionary implications of persistent… read more here.
Keywords: alteration liver; transient elastography; liver; persistent alteration ... See more keywords
GP274 Liver tests in F508del homozygous cystic fibrosis patients on orkambi
Sign Up to like & getrecommendations! Published in 2019 at "Archives of Disease in Childhood"
DOI: 10.1136/archdischild-2019-epa.333
Abstract: Aims Cystic Fibrosis (CF) is an inherited condition causing complex, multi-system disease. Ireland has the highest incidence of CF in the world, where one in 19 people carry a defective gene. The most common detected… read more here.
Keywords: patients orkambi; cystic fibrosis; treatment; liver tests ... See more keywords