Cost‐effectiveness of liver transplantation in patients with colorectal metastases confined to the liver
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DOI: 10.1002/bjs.10962
Abstract: Patients with non‐resectable colorectal metastases are currently treated with chemotherapy. However, liver transplantation can increase the 5‐year survival rate from 9 to 56 per cent if the cancer is confined to the liver. The aim… read more here.
Keywords: confined liver; effectiveness liver; colorectal metastases; transplantation ... See more keywords
Short‐ and long‐term mortality after liver transplantation in patients with and without hepatocellular carcinoma in the UK
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DOI: 10.1002/bjs.11451
Abstract: The increasing demand for liver transplantation has led to considerable changes in characteristics of donors and recipients. This study evaluated the short‐ and long‐term mortality of recipients with and without hepatocellular carcinoma (HCC) in the… read more here.
Keywords: hepatocellular carcinoma; long term; short long; liver transplantation ... See more keywords
Hypothyroidism is associated with worse outcomes of hepatocellular carcinoma patients after liver transplantation
Sign Up to like & getrecommendations! Published in 2018 at "Cancer Medicine"
DOI: 10.1002/cam4.1797
Abstract: Hypothyroidism has been associated with hepatocellular carcinoma (HCC) incidence; however, the relationship between hypothyroidism and HCC patient outcomes is unclear. We investigated the impact of hypothyroidism on outcomes after liver transplantation for HCC. read more here.
Keywords: hepatocellular carcinoma; hypothyroidism; hypothyroidism associated; liver transplantation ... See more keywords
Efficacy and safety of lenvatinib in patients with recurrent hepatocellular carcinoma after liver transplantation
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DOI: 10.1002/cam4.5123
Abstract: Lenvatinib is approved for the treatment of patients with metastatic or recurrent hepatocellular carcinoma (HCC); however, clinical outcomes of lenvatinib therapy in patients with post‐liver transplantation (LT) HCC recurrence remain unclear. We investigated the efficacy… read more here.
Keywords: hepatocellular carcinoma; safety lenvatinib; lenvatinib; recurrent hepatocellular ... See more keywords
Advances in Liver Transplantation: where are we in the pursuit of transplantation tolerance?
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DOI: 10.1002/eji.202048875
Abstract: Liver transplantation is the ultimate treatment option for end‐stage liver disease. Breakthroughs in surgical practice and immunosuppression have seen considerable advancements in survival after transplantation. However, the intricate management of immunosuppressive regimens, balancing desired immunological… read more here.
Keywords: pursuit transplantation; advances liver; transplantation pursuit; tolerance ... See more keywords
Liver transplantation for hepatocellular carcinoma through the lens of transplant benefit
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DOI: 10.1002/hep.28998
Abstract: One of the crucial objectives in medicine is to assess and quantify the benefit of a therapeutic approach to a given clinical condition in order to avoid delivering potentially harmful treatments (when the risk is… read more here.
Keywords: liver transplantation; waiting list; benefit; transplant benefit ... See more keywords
Intention‐to‐treat survival benefit in liver transplantation: Comments on Lai et al.
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DOI: 10.1002/hep.29755
Abstract: model selections is no different, and effect estimates are largely unchanged. We also agree with Ridola and Riggio that the presence of minimal HE is predictive of incident overt HE. However, minimal HE is not… read more here.
Keywords: survival benefit; benefit liver; intention treat; liver transplantation ... See more keywords
Is It Time to Reconsider the Milan Criteria for Selecting Patients With Hepatocellular Carcinoma for Deceased‐Donor Liver Transplantation?
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DOI: 10.1002/hep.30278
Abstract: Liver transplantation (LT) is considered the optimal treatment for hepatocellular carcinoma (HCC) because it removes tumor as well as the underlying cirrhotic liver. Because of a global organ shortage, LT for patients with HCC is… read more here.
Keywords: hepatocellular carcinoma; milan criteria; patients hcc; liver transplantation ... See more keywords
Assessing the Time‐Dependent Impact of Performance Status on Outcomes After Liver Transplantation
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DOI: 10.1002/hep.31124
Abstract: Identifying how the prognostic impact of performance status (PS) differs according to indication, era, and time period (“epoch”) after liver transplantation (LT) could have implications for selection and treatment of patients on the waitlist. We… read more here.
Keywords: performance status; impact; liver transplantation; impact performance ... See more keywords
Simultaneous Heart–Liver Transplantation for Congenital Heart Disease in the United States: Rapidly Increasing With Acceptable Outcomes
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DOI: 10.1002/hep.31426
Abstract: There are more adults than children living with congenital heart disease (CHD) in the United States, with a growing proportion requiring heart–liver transplantation (HLT). Our aim was to ascertain the frequency, outcomes, and prognostic factors… read more here.
Keywords: heart; heart liver; heart disease; liver transplantation ... See more keywords
Donor Hepatic Occult Collagen Deposition Predisposes to Peritransplant Stress and Impacts Human Liver Transplantation
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DOI: 10.1002/hep.32030
Abstract: Environmentally triggered chronic liver inflammation can cause collagen deposits, whereas early stages of fibrosis without any specific symptoms could hardly be detectable. We hypothesized that some of the human donor grafts in clinical liver transplantation… read more here.
Keywords: collagen; donor hepatic; liver transplantation; hepatic occult ... See more keywords