Multi‐Targeted Peptide‐Modified Gold Nanoclusters for Treating Solid Tumors in the Liver
Sign Up to like & getrecommendations! Published in 2023 at "Advanced Materials"
DOI: 10.1002/adma.202210412
Abstract: Apoptosis and autophagy determine the fate of cancer cells. However, simply promoting apoptosis of tumor cells is limited in the treatment of unresectable solid liver tumors. Generally, autophagy is considered the anti‐apoptotic “guardian”. But the… read more here.
Keywords: modified gold; liver; liver tumors; peptide modified ... See more keywords
Conspicuity of Malignant Liver Tumors on Diffusion‐Weighted Imaging With Short tau Inversion Recovery After Gadolinium Ethoxybenzyl Diethylenetriaminepentaacetic Acid Administration
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Magnetic Resonance Imaging"
DOI: 10.1002/jmri.26196
Abstract: Diffusion‐weighted imaging (DWI) has been used for the detection and characterization of liver tumors because it has excellent contrast resolution. DWI using short tau inversion recovery (STIR) can improve tumor‐to‐liver contrast after gadolinium ethoxybenzyl diethylenetriaminepentaacetic… read more here.
Keywords: weighted imaging; short tau; inversion recovery; liver tumors ... See more keywords
Specialized computational methods for denoising, B1 correction, and kinetic modeling in hyperpolarized 13C MR EPSI studies of liver tumors
Sign Up to like & getrecommendations! Published in 2021 at "Magnetic Resonance in Medicine"
DOI: 10.1002/mrm.28901
Abstract: To develop a novel post‐processing pipeline for hyperpolarized (HP) 13C MRSI that integrates tensor denoising and B1+ correction to measure pyruvate‐to‐lactate conversion rates (kPL) in patients with liver tumors. read more here.
Keywords: specialized computational; liver tumors; denoising correction; hyperpolarized 13c ... See more keywords
Radiological diagnostic workup of liver tumors
Sign Up to like & getrecommendations! Published in 2020 at "Der Internist"
DOI: 10.1007/s00108-019-00724-9
Abstract: The imaging of focal liver lesions is a common task in daily radiological routine. The objectives of diagnostic imaging are, in addition to lesion detection, the characterization of the lesion as well as the follow-up… read more here.
Keywords: workup liver; liver; radiological diagnostic; liver lesions ... See more keywords
Parenchymal preserving liver resection for centrally located liver tumors: how I do it?
Sign Up to like & getrecommendations! Published in 2021 at "Langenbeck's Archives of Surgery"
DOI: 10.1007/s00423-021-02313-7
Abstract: Central liver tumors often require extended hepatectomy or a central hepatectomy with complex biliary reconstructions. Extended resections are prone to higher chances of post-operative liver failure, while the resections mandating reconstructions run a risk of… read more here.
Keywords: centrally located; liver resection; located liver; liver ... See more keywords
Nanoparticle-Mediated Delivery of 2-Deoxy-D-Glucose Induces Antitumor Immunity and Cytotoxicity in Liver Tumors in Mice
Sign Up to like & getrecommendations! Published in 2020 at "Cellular and Molecular Gastroenterology and Hepatology"
DOI: 10.1016/j.jcmgh.2020.10.010
Abstract: Background & Aims Immune checkpoint inhibitors have shed light on the importance of antitumor immunity as a therapeutic strategy for hepatocellular carcinoma (HCC). The altered glucose metabolism known as the Warburg effect recently has gained… read more here.
Keywords: antitumor immunity; plga nps; liver tumors; 2dg plga ... See more keywords
Predicting Therapeutic Efficacy of Vascular Disrupting Agent CA4P in Rats with Liver Tumors by Hepatobiliary Contrast Agent Mn-DPDP-Enhanced MRI
Sign Up to like & getrecommendations! Published in 2019 at "Translational Oncology"
DOI: 10.1016/j.tranon.2019.09.010
Abstract: To evaluate hepatobiliary-specific contrast agent (CA) mangafodipir trisodium (Mn-DPDP)–enhanced magnetic resonance imaging (MRI) for predicting the therapeutic efficacy of the vascular disrupting agent combretastatin A4 phosphate (CA4P) in rats with primary and secondary liver tumors,… read more here.
Keywords: agent; dpdp enhanced; ca4p; liver tumors ... See more keywords
Update: Mode of action (MOA) for liver tumors induced by oral exposure to 1,4‐dioxane
Sign Up to like & getrecommendations! Published in 2017 at "Regulatory Toxicology and Pharmacology"
DOI: 10.1016/j.yrtph.2017.02.025
Abstract: ABSTRACT Previous work has shown that the weight of evidence supports the hypothesis that 1,4‐dioxane causes liver tumors in rodents through cytotoxicity and subsequent regenerative hyperplasia. Questions regarding a lack of concordant findings for this… read more here.
Keywords: liver; liver tumors; dioxane; moa ... See more keywords
Investigation of the mechanism of triclosan induced mouse liver tumors
Sign Up to like & getrecommendations! Published in 2017 at "Regulatory Toxicology and Pharmacology"
DOI: 10.1016/j.yrtph.2017.03.001
Abstract: &NA; Chronic dietary exposure to Triclosan (TCS) produced increased incidence of liver tumors in mice. The mechanism for liver tumor induction has been attributed to activation of either peroxisome proliferator activated receptor &agr; (PPAR&agr;) or… read more here.
Keywords: liver tumors; ppar agr; car; liver ... See more keywords
Immunosuppression in liver tumors: opening the portal to effective immunotherapy
Sign Up to like & getrecommendations! Published in 2017 at "Cancer Gene Therapy"
DOI: 10.1038/cgt.2016.54
Abstract: We have recently witnessed substantial progress with immunotherapy for selected diseases. Checkpoint inhibitors and chimeric antigen receptor T (CAR-T) cells are among the most promising agents. Whereas much of the early success with CAR-T cells… read more here.
Keywords: opening portal; immunosuppression liver; immunotherapy; tumors opening ... See more keywords
Percutaneous Irreversible Electroporation: Long-term survival analysis of 71 patients with inoperable malignant hepatic tumors
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/srep43687
Abstract: Aim of this retrospective analysis was to evaluate the survival times after percutaneous irreversible electroporation (IRE) in inoperable liver tumors not amenable to thermal ablation. 71 patients (14 females, 57 males, median age 63.5 ± 10.8 years)… read more here.
Keywords: irreversible electroporation; percutaneous irreversible; analysis; liver tumors ... See more keywords