Expanding the search for genetic biomarkers of Parkinson's disease into the living brain
Sign Up to like & getrecommendations! Published in 2020 at "Neurobiology of Disease"
DOI: 10.1016/j.nbd.2020.104872
Abstract: Altered gene expression related to Parkinson's Disease (PD) has not been described in the living brain, yet this information may support novel discovery pertinent to disease pathophysiology and treatment. This study compared the transcriptome in… read more here.
Keywords: control patients; parkinson disease; brain; living brain ... See more keywords
Aberration correction in stimulated emission depletion microscopy to increase imaging depth in living brain tissue
Sign Up to like & getrecommendations! Published in 2021 at "Neurophotonics"
DOI: 10.1117/1.nph.8.3.035001
Abstract: Abstract. Significance: Stimulated emission depletion (STED) microscopy enables nanoscale imaging of live samples, but it requires a specific spatial beam shaping that is highly sensitive to optical aberrations, limiting its depth penetration. Therefore, there is… read more here.
Keywords: imaging depth; microscopy; correction; living brain ... See more keywords
Methods for Quantifying Neurotransmitter Dynamics in the Living Brain With PET Imaging
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Physiology"
DOI: 10.3389/fphys.2020.00792
Abstract: Positron emission tomography (PET) neuroimaging in neuropsychiatry is a powerful tool for the quantification of molecular brain targets to characterize disease, assess disease subtype differences, evaluate short- and long-term effects of treatments, or even to… read more here.
Keywords: living brain; dynamics living; neurotransmitter dynamics; quantifying neurotransmitter ... See more keywords