Living Cell Materials for Advanced Biomedical Applications in Disease Diagnosis, Treatment, and Prevention
Sign Up to like & getrecommendations! Published in 2025 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.202502358
Abstract: Tailored and personalized therapies have gained significant attention for their great potential to minimize treatment‐related side effects, mitigate immunological rejection, and improve disease prognosis. In this context, living cell materials (LCMs)—comprising living cells integrated with… read more here.
Keywords: treatment; disease diagnosis; cell; living cell ... See more keywords
Jammed Micro‐Flake Hydrogel for Four‐Dimensional Living Cell Bioprinting
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Materials"
DOI: 10.1002/adma.202109394
Abstract: 4D bioprinting is promising to build cell‐laden constructs (bioconstructs) with complex geometries and functions for tissue/organ regeneration applications. The development of hydrogel‐based 4D bioinks, especially those allowing living cell printing, with easy preparation, defined composition,… read more here.
Keywords: living cell; cell; micro flake; flake hydrogel ... See more keywords
Extending applications of AFM to fluidic AFM in single living cell studies
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.30809
Abstract: In this article, a review of a series of applications of atomic force microscopy (AFM) and fluidic Atomic Force Microscopy (fluidic AFM, hereafter fluidFM) in single‐cell studies is presented. AFM applications involving single‐cell and extracellular… read more here.
Keywords: living cell; cell; afm; microscopy ... See more keywords
Ratiometric two-photon fluorescence probes for sensing, imaging and biomedicine applications at living cell and small animal levels
Sign Up to like & getrecommendations! Published in 2021 at "Coordination Chemistry Reviews"
DOI: 10.1016/j.ccr.2021.214114
Abstract: Abstract The unique two-photon excitable luminescence and dual-emission ratio output features endow organic molecule- based ratiometric two-photon fluorescence (RTPF) probes as powerful and versatile analysis tools with promising biological and biomedical applications, especially in target… read more here.
Keywords: two photon; photon fluorescence; ratiometric two; rtpf probes ... See more keywords
Binding-induced nicking site reconstruction strategy for quantitative detection of membrane protein on living cell.
Sign Up to like & getrecommendations! Published in 2018 at "Talanta"
DOI: 10.1016/j.talanta.2018.06.030
Abstract: Here, a binding-induced nicking site reconstruction strategy has been fabricated for quantitative detection of membrane protein on living cell. Taking protein tyrosine kinase-7 (PTK7) as model analyst, first, an aptamer probe was designed with an… read more here.
Keywords: reconstruction; nicking site; living cell; site ... See more keywords
Self-Referenced Nanopipette for Electrochemical Analysis of Hydrogen Peroxide in the Nucleus of a Single Living Cell.
Sign Up to like & getrecommendations! Published in 2021 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.0c05025
Abstract: In a typical intracellular electroanalytical measurement, a nanoelectrode is located inside a living cell and a reference electrode outside the cell. This setup faces a problem to drop a certain potential across the cellular plasma… read more here.
Keywords: hydrogen peroxide; living cell; cell; self referenced ... See more keywords
Living Cell-Target Responsive Accessibility Profiling Reveals Silibinin Targeting ACSL4 for Combating Ferroptosis.
Sign Up to like & getrecommendations! Published in 2022 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.2c03515
Abstract: We report a living cell-target responsive accessibility profiling (LC-TRAP) approach to identify the targetome of silibinin (SIL), a well-established hepatoprotective natural product (NP), in HepG2 cells. Proteins showing accessibility changes, probed by covalent lysine labeling… read more here.
Keywords: living cell; cell target; accessibility; ferroptosis ... See more keywords
Single-Nucleobase-Resolved Nanoruler Determines the Surface Energy Transfer Radius on the Living Cell Membrane.
Sign Up to like & getrecommendations! Published in 2024 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.4c00128
Abstract: Investigations about surface energy transfer radius (r0) are limited to the aqueous solution system, and it is quite limited on experimental values of r0 between dyes and the corresponding gold particle (AuNP) sizes, especially for… read more here.
Keywords: nucleobase resolved; surface energy; cell; energy transfer ... See more keywords
Rapid MS-Based Single-Cell Analysis Assisted by Photochemical Derivatization in Living Cell Membranes Reveals Lipidomic Patterns with Located C═C Bonds.
Sign Up to like & getrecommendations! Published in 2025 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.5c01725
Abstract: Traditional lipidomics methods are not well-suited for studying unsaturated lipids containing located C═C bonds in single cells. Here, we proposed a single-cell mass spectrometry (MS) platform assisted by a photochemical derivatization (PCD) method termed Visible-light-activated… read more here.
Keywords: single cell; located bonds; cell membranes; cell ... See more keywords
Electrochemical Molecule Trap-Based Sensing of Low-Abundance Enzymes in One Living Cell.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.2c06962
Abstract: Measuring the activity of low-abundance enzymes, down to a few molecules in one living cell, is important but challenging to elucidate their biological function. Here, an electrochemical molecule trap is established at the tip of… read more here.
Keywords: living cell; molecule; low abundance; electrochemical molecule ... See more keywords
Spatially Quantitative Imaging of Enzyme Activity in a Living Cell.
Sign Up to like & getrecommendations! Published in 2024 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.4c14190
Abstract: Enzyme activity plays a key role in cell heterogeneity. Its spatially quantitative imaging in a living cell not only directly displays but also helps people to understand cell heterogeneity. Current methods are hard to achieve… read more here.
Keywords: spatially quantitative; cell; quantitative imaging; living cell ... See more keywords