Mechanosensitive molecular mechanisms of myocardial fibrosis in living myocardial slices
Sign Up to like & getrecommendations! Published in 2022 at "ESC Heart Failure"
DOI: 10.1002/ehf2.13832
Abstract: Altered mechanical load in response to injury is a main driver of myocardial interstitial fibrosis. No current in vitro model can precisely modulate mechanical load in a multicellular environment while maintaining physiological behaviour. Living myocardial… read more here.
Keywords: myocardial slices; myocardial fibrosis; molecular mechanisms; mechanosensitive molecular ... See more keywords
Living myocardial slices: Advancing arrhythmia research
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Physiology"
DOI: 10.3389/fphys.2023.1076261
Abstract: Living myocardial slices (LMS) are ultrathin (150–400 µm) sections of intact myocardium that can be used as a comprehensive model for cardiac arrhythmia research. The recent introduction of biomimetic electromechanical cultivation chambers enables long-term cultivation… read more here.
Keywords: arrhythmia research; myocardial slices; slices advancing; living myocardial ... See more keywords