LKB1 expression and the prognosis of lung cancer
Sign Up to like & getrecommendations! Published in 2021 at "Medicine"
DOI: 10.1097/md.0000000000027841
Abstract: Abstract Background: In the past few decades, many lines of evidence implicate the importance of liver kinase B1 (LKB1) as a tumor suppressor gene in the development and progression of solid tumours. However, the prognostic… read more here.
Keywords: expression; lung cancer; lkb1 expression;
Association Between the Efficacy of Pembrolizumab and Low STK11/LKB1 Expression in High-PD-L1-expressing Non-small-cell Lung Cancer
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DOI: 10.21873/invivo.12131
Abstract: Background/Aim: STK11/LKB1 mutation has been suggested as a poorly responding candidate biomarker of the anti-programmed cell death-1 (PD-1) antibody; however, the association between STK11/LKB1 expression and the effects of anti-PD-1 antibodies is uncertain. The aim… read more here.
Keywords: stk11; low stk11; lkb1 expression; stk11 lkb1 ... See more keywords
Liver Kinase B1—A Potential Therapeutic Target in Hormone-Sensitive Breast Cancer in Older Women
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DOI: 10.3390/cancers11020149
Abstract: Background: The role of liver kinase B1 (LKB1), a serine/threonine kinase, has been described in the development of PeutzJagher’s syndrome, where a proportion (~45%) of patients have developed breast cancer in their lifetime. Cell line… read more here.
Keywords: expression; lkb1 expression; older women; breast cancer ... See more keywords
Downregulation of LKB1 promotes tumor progression and predicts unfavorable prognosis in patients with glioma
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DOI: 10.3892/ol.2017.5631
Abstract: The liver kinase B1 (LKB1)/5′-adenosine monophosphate-activated protein kinase pathway has been reported to facilitate glioma cell growth by improving growth conditions. To investigate the clinical significance of LKB1 in human gliomas western blot analysis and… read more here.
Keywords: patients glioma; expression; lkb1 expression; downregulation lkb1 ... See more keywords