Liver-specific deletion of LASS2 delayed regeneration of mouse liver after partial hepatectomy.
Sign Up to like & getrecommendations! Published in 2017 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2017.09.128
Abstract: The capacity of liver regeneration is critical for patients with liver diseases. However, cellular and molecular mechanisms of liver regeneration are still incompletely defined. Here, we assessed roles of LASS2 in liver regeneration following partial… read more here.
Keywords: lko mice; liver regeneration; regeneration; lass2 lko ... See more keywords
Regulation of Hepatic Gluconeogenesis by Nuclear Receptor Coactivator 6
Sign Up to like & getrecommendations! Published in 2022 at "Molecules and Cells"
DOI: 10.14348/molcells.2022.2222
Abstract: Nuclear receptor coactivator 6 (NCOA6) is a transcriptional coactivator of nuclear receptors and other transcription factors. A general Ncoa6 knockout mouse was previously shown to be embryonic lethal, but we here generated liver-specific Ncoa6 knockout… read more here.
Keywords: nuclear receptor; coactivator; lko mice; receptor coactivator ... See more keywords
Hepatocyte-Specific Phgdh-Deficient Mice Culminate in Mild Obesity, Insulin Resistance, and Enhanced Vulnerability to Protein Starvation
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DOI: 10.3390/nu13103468
Abstract: l-Serine (Ser) is synthesized de novo from 3-phosphoglycerate via the phosphorylated pathway committed by phosphoglycerate dehydrogenase (Phgdh). A previous study reported that feeding a protein-free diet increased the enzymatic activity of Phgdh in the liver… read more here.
Keywords: protein; protein starvation; lko mice; mice ... See more keywords