Reconstructing Three‐Dimensional Optical Anisotropy with Tomographic Müller‐Polarimetric Microscopy
Sign Up to like & getrecommendations! Published in 2025 at "Advanced Science"
DOI: 10.1002/advs.202502075
Abstract: Most visible light imaging methods using polarization to obtain ultrastructure information are limited to 2D analysis or require demanding phase measurements to be extended to 3D. A novel 3D polarized light imaging technique based on… read more here.
Keywords: tomographic ller; ller polarimetric; polarimetric microscopy; ller ... See more keywords
The impact of sestrin2 on reactive oxygen species in diabetic retinopathy
Sign Up to like & getrecommendations! Published in 2024 at "Cell Biochemistry and Function"
DOI: 10.1002/cbf.4024
Abstract: Diabetic retinopathy (DR) is a significant complication of diabetes that often leads to blindness, impacting Müller cells, the primary retinal macroglia involved in DR pathogenesis. Reactive oxygen species (ROS) play a crucial role in the… read more here.
Keywords: sestrin2; oxygen species; diabetic retinopathy; reactive oxygen ... See more keywords
Microglial‐induced Müller cell gliosis is attenuated by progesterone in a mouse model of retinitis pigmentosa
Sign Up to like & getrecommendations! Published in 2018 at "Glia"
DOI: 10.1002/glia.23243
Abstract: Norgestrel, a progesterone analogue, has demonstrated neuroprotective effects in a mouse model of retinitis pigmentosa. Neuroprotection is achieved in part through Norgestrels anti‐inflammatory properties, alleviating detrimental microglial activity. Gliosis is a feature of many neurodegenerative… read more here.
Keywords: ller; gliosis; retinitis pigmentosa; cell gliosis ... See more keywords
Compensatory engulfment and Müller glia reactivity in the absence of microglia.
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DOI: 10.1002/glia.24182
Abstract: Microglia are known for important phagocytic functions in the vertebrate retina. Reports also suggest that Müller glia have phagocytic capacity, though the relative levels and contexts in which this occurs remain to be thoroughly examined.… read more here.
Keywords: ller; engulfment; ller glia; absence microglia ... See more keywords
Retinal regions shape human and murine Müller cell proteome profile and functionality
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DOI: 10.1002/glia.24283
Abstract: The human macula is a highly specialized retinal region with pit‐like morphology and rich in cones. How Müller cells, the principal glial cell type in the retina, are adapted to this environment is still poorly… read more here.
Keywords: cell; retinal regions; ller; ller cell ... See more keywords
Regulating the formation of Müller glia‐derived progenitor cells in the retina
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DOI: 10.1002/glia.24635
Abstract: We summarize recent findings in different animal models regarding the different cell‐signaling pathways and gene networks that influence the reprogramming of Müller glia into proliferating, neurogenic progenitor cells in the retina. Not surprisingly, most of… read more here.
Keywords: cells retina; ller; progenitor cells; ller glia ... See more keywords
Hydrogen peroxide modulates energy metabolism and oxidative stress in cultures of permanent human Müller cells MIO-M1.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of biophotonics"
DOI: 10.1002/jbio.201600201
Abstract: In this study the influence of hydrogen peroxide (H2 O2 ) on the redox state, NADH protein binding, and mitochondrial membrane potential in Müller cells is investigated. Cultures of permanent human Müller cells MIO-M1 were… read more here.
Keywords: cultures permanent; ller; human ller; hydrogen peroxide ... See more keywords
Thioredoxin 1 overexpression attenuated diabetes‐induced endoplasmic reticulum stress in Müller cells via apoptosis signal‐regulating kinase 1
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.30378
Abstract: As one of the common and serious chronic complications of diabetes mellitus (DM), the related mechanism of diabetic retinopathy (DR) has not been fully understood. Müller cell reactive gliosis is one of the early pathophysiological… read more here.
Keywords: apoptosis signal; ller; overexpression; signal regulating ... See more keywords
Spontaneously Immortalised Nonhuman Primate Müller Glia Cell Lines as Source to Explore Retinal Reprogramming Mechanisms for Cell Therapies
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.31482
Abstract: Cell replacement therapies for ocular diseases characterised by photoreceptors degeneration are challenging due to poor primary cell survival in culture. A stable retinal cell source to replace lost photoreceptors holds promise. Müller glia cells play… read more here.
Keywords: glia cell; culture; cell; ller glia ... See more keywords
Human glial müller and umbilical vein endothelial cell coculture as an in vitro model to investigate retinal oxidative damage. A morphological and molecular assessment
Sign Up to like & getrecommendations! Published in 2022 at "Microscopy Research and Technique"
DOI: 10.1002/jemt.24284
Abstract: The aim of this study was to optimize a coculture in vitro model established between the human Müller glial cells and human umbilical vein endothelial cells, mimicking the inner blood‐retinal barrier, and to explore its… read more here.
Keywords: cell; ller; model; coculture ... See more keywords
Release of VAMP5‐positive extracellular vesicles by retinal Müller glia in vivo
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Extracellular Vesicles"
DOI: 10.1002/jev2.12254
Abstract: Cell-cell interactions in the central nervous system are based on the release of molecules mediating signal exchange and providing structural and trophic support through vesicular exocytosis and the formation of extracellular vesicles. The specific mechanisms… read more here.
Keywords: vivo; extracellular vesicles; ller; retinal ller ... See more keywords