Glia of the human retina
Sign Up to like & getrecommendations! Published in 2019 at "Glia"
DOI: 10.1002/glia.23727
Abstract: The human retina contains three types of glial cells: microglia and two types of macroglia, astrocytes and Müller cells. Macroglia provide homeostatic and metabolic support to photoreceptors and neurons required for neuronal activity. The fovea,… read more here.
Keywords: glia human; human retina; retina; ller cells ... See more keywords
Retinal regions shape human and murine Müller cell proteome profile and functionality
Sign Up to like & getrecommendations! Published in 2022 at "Glia"
DOI: 10.1002/glia.24283
Abstract: The human macula is a highly specialized retinal region with pit‐like morphology and rich in cones. How Müller cells, the principal glial cell type in the retina, are adapted to this environment is still poorly… read more here.
Keywords: cell; retinal regions; ller; ller cell ... See more keywords
Hydrogen peroxide modulates energy metabolism and oxidative stress in cultures of permanent human Müller cells MIO-M1.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of biophotonics"
DOI: 10.1002/jbio.201600201
Abstract: In this study the influence of hydrogen peroxide (H2 O2 ) on the redox state, NADH protein binding, and mitochondrial membrane potential in Müller cells is investigated. Cultures of permanent human Müller cells MIO-M1 were… read more here.
Keywords: cultures permanent; ller; human ller; hydrogen peroxide ... See more keywords
Thioredoxin 1 overexpression attenuated diabetes‐induced endoplasmic reticulum stress in Müller cells via apoptosis signal‐regulating kinase 1
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.30378
Abstract: As one of the common and serious chronic complications of diabetes mellitus (DM), the related mechanism of diabetic retinopathy (DR) has not been fully understood. Müller cell reactive gliosis is one of the early pathophysiological… read more here.
Keywords: apoptosis signal; ller; overexpression; signal regulating ... See more keywords
Specific ablation of Hippo signalling component Yap1 in retinal progenitors and Müller cells results in late onset retinal degeneration
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.30757
Abstract: Yes‐associated protein (YAP) is a major component of the Hippo pathway involved in development, growth, repair and homeostasis. Nonsense YAP1 mutations in humans result in autosomal dominant coloboma. Here, we generated a conditional knockout mouse… read more here.
Keywords: degeneration; retinal degeneration; onset retinal; hippo ... See more keywords
Release of VAMP5‐positive extracellular vesicles by retinal Müller glia in vivo
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Extracellular Vesicles"
DOI: 10.1002/jev2.12254
Abstract: Cell-cell interactions in the central nervous system are based on the release of molecules mediating signal exchange and providing structural and trophic support through vesicular exocytosis and the formation of extracellular vesicles. The specific mechanisms… read more here.
Keywords: vivo; extracellular vesicles; ller; retinal ller ... See more keywords
Probucol promotes high glucose-induced proliferation and inhibits apoptosis by reducing reactive oxygen species generation in Müller cells
Sign Up to like & getrecommendations! Published in 2019 at "International Ophthalmology"
DOI: 10.1007/s10792-019-01130-8
Abstract: PurposeTo explore the protective effect of probucol on human retinal Müller cells cultured in high glucose.MethodsPrimary Müller cells from human retinas were cultured in complete DMEM. Third-generation Müller cells were identified using glutamine synthetase (GS)… read more here.
Keywords: ller; proliferation; ller cells; high glucose ... See more keywords
Extrafoveal müller cells detection in vivo in the human retina: A pilot study based on optical coherence tomography.
Sign Up to like & getrecommendations! Published in 2020 at "Experimental eye research"
DOI: 10.1016/j.exer.2020.108183
Abstract: Müller cells (MC) represent a key element for the metabolic and functional regulation of the vertebrate retina. The aim of the present study was to test the feasibility of a new method for the in-vivo… read more here.
Keywords: detection; human retina; study; ller cells ... See more keywords
Spatial and temporal immunoreaction of nestin, CD44, collagen IX and GFAP in human retinal Müller cells in the developing fetal eye.
Sign Up to like & getrecommendations! Published in 2022 at "Experimental eye research"
DOI: 10.1016/j.exer.2022.108958
Abstract: The purpose of this study was to investigate Müller cells during the fetal development of the human eye. Müller cells in eyes of 39 human fetuses (11-38 weeks of gestation, WOG) and 6 infants (5… read more here.
Keywords: ller; eye; collagen; nestin ... See more keywords
Müller cells and astrocytes in tractional macular disorders
Sign Up to like & getrecommendations! Published in 2021 at "Progress in retinal and eye research"
DOI: 10.1016/j.preteyeres.2021.100977
Abstract: Tractional deformations of the fovea mainly arise from an anomalous posterior vitreous detachment and contraction of epiretinal membranes, and also occur in eyes with cystoid macular edema or high myopia. Traction to the fovea may… read more here.
Keywords: ller; macular disorders; ller cells; fovea ... See more keywords
Müller cells in pathological retinal angiogenesis
Sign Up to like & getrecommendations! Published in 2019 at "Translational Research"
DOI: 10.1016/j.trsl.2018.12.006
Abstract: &NA; Müller cells are the major glial cells spanning the entire layer of the retina and maintaining retinal structure. Under pathological conditions, Müller cells are involved in retinal angiogenesis, a process of growing new blood… read more here.
Keywords: cells pathological; pathological retinal; retinal angiogenesis; ller cells ... See more keywords