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   Articles with "ller glia" as a keyword



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NFkB‐signaling promotes glial reactivity and suppresses Müller glia‐mediated neuron regeneration in the mammalian retina

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recommendations! Published in 2022 at "Glia"

DOI: 10.1002/glia.24181

Abstract: Müller glia (MG) in mammalian retinas are incapable of regenerating neurons after damage, whereas the MG in lower vertebrates regenerate functional neurons. Identification of cell signaling pathways and gene regulatory networks that regulate MG‐mediated regeneration… read more here.

Keywords: regeneration; ller glia; glia; damage ... See more keywords
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Compensatory engulfment and Müller glia reactivity in the absence of microglia.

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recommendations! Published in 2022 at "Glia"

DOI: 10.1002/glia.24182

Abstract: Microglia are known for important phagocytic functions in the vertebrate retina. Reports also suggest that Müller glia have phagocytic capacity, though the relative levels and contexts in which this occurs remain to be thoroughly examined.… read more here.

Keywords: ller; engulfment; ller glia; absence microglia ... See more keywords
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Pten associates with important gene regulatory network to fine‐tune Müller glia‐mediated zebrafish retina regeneration

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recommendations! Published in 2022 at "Glia"

DOI: 10.1002/glia.24270

Abstract: Unlike mammals, zebrafish possess a remarkable ability to regenerate damaged retina after an acute injury. Retina regeneration in zebrafish involves the induction of Müller glia‐derived progenitor cells (MGPCs) exhibiting stem cell‐like characteristics, which are capable… read more here.

Keywords: zebrafish retina; ller glia; retina; retina regeneration ... See more keywords
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Modeling of Photoreceptor Donor‐Host Interaction Following Transplantation Reveals a Role for Crx, Müller Glia, and Rho/ROCK Signaling in Neurite Outgrowth

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recommendations! Published in 2019 at "STEM CELLS"

DOI: 10.1002/stem.2985

Abstract: The goal of photoreceptor transplantation is to establish functional synaptic connectivity between donor cells and second‐order neurons in the host retina. There is, however, limited evidence of donor‐host photoreceptor connectivity post‐transplant. In this report, we… read more here.

Keywords: donor host; ller glia; donor; neurite outgrowth ... See more keywords
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Müller Glia Reactivity and Development of Gliosis in Response to Pathological Conditions.

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recommendations! Published in 2018 at "Advances in experimental medicine and biology"

DOI: 10.1007/978-3-319-75402-4_37

Abstract: Within the mammalian retina, both Müller glia and astrocytes display reactivity in response to many forms of retinal injury and disease in a process termed gliosis. Reactive gliosis is a complex process that is considered… read more here.

Keywords: response; ller glia; pathological conditions; gliosis ... See more keywords
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Müller Glia-Mediated Retinal Regeneration.

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recommendations! Published in 2021 at "Molecular neurobiology"

DOI: 10.1007/s12035-020-02274-w

Abstract: Müller glia originate from neuroepithelium and are the principal glial cells in the retina. During retinal development, Müller glia are one of the last cell types to be born. In lower vertebrates, such as zebrafish,… read more here.

Keywords: glia reprogramming; ller; retinal regeneration; ller glia ... See more keywords
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The miR-216a-Dot1l Regulatory Axis Is Necessary and Sufficient for Müller Glia Reprogramming during Retina Regeneration

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recommendations! Published in 2019 at "Cell reports"

DOI: 10.1016/j.celrep.2019.07.061

Abstract: SUMMARY Unlike the adult mammalian retina, Müller glia (MG) in the adult zebrafish retina are able to dedifferentiate into a ‘‘stem cell’’-like state and give rise to multipotent progenitor cells upon retinal damage. We show… read more here.

Keywords: ller glia; retina regeneration; mir 216a; regeneration ... See more keywords
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MicroRNA-28 potentially regulates the photoreceptor lineage commitment of Müller glia-derived progenitors

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recommendations! Published in 2017 at "Scientific Reports"

DOI: 10.1038/s41598-017-11112-4

Abstract: Retinal degenerative diseases ultimately result into irreversible photoreceptor death or loss. At present, the most promising treatment for these diseases is cell replacement therapy. Müller glia are the major glia in the retina, displaying cardinal… read more here.

Keywords: ller; glia derived; ller glia; mir ... See more keywords
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Vegf signaling between Müller glia and vascular endothelial cells is regulated by immune cells and stimulates retina regeneration.

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recommendations! Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"

DOI: 10.1073/pnas.2211690119

Abstract: Significance Degeneration of retinal neurons underlies a variety of blinding eye diseases. Thus, restoring lost neurons is a major goal of vision scientists. One approach is to use endogenous stem cells to regenerate damaged retinal… read more here.

Keywords: ller glia; endothelial cells; immune cells; vascular endothelial ... See more keywords
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Potential of Müller Glia for Retina Neuroprotection

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recommendations! Published in 2019 at "Current Eye Research"

DOI: 10.1080/02713683.2019.1648831

Abstract: ABSTRACT Müller glia constitute the main glial cells of the retina. They are spatially distributed along this tissue, facilitating their close membrane interactions with all retinal neurons. Müller glia are characterized by their active metabolic… read more here.

Keywords: ller; glia retina; ller glia; potential ller ... See more keywords
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Patterns of NFkB activation resulting from damage, reactive microglia, cytokines, and growth factors in the mouse retina

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recommendations! Published in 2022 at "Experimental Neurology"

DOI: 10.1101/2022.08.16.504164

Abstract: Müller glia are a cellular source for neuronal regeneration in vertebrate retinas. However, the capacity for retinal regeneration varies widely across species. Understanding the mechanisms that regulate the reprogramming of Müller glia into progenitor cells… read more here.

Keywords: ller glia; damage; ller; reactive microglia ... See more keywords