Müller glial cell reactivation in Xenopus models of retinal degeneration
Sign Up to like & getrecommendations! Published in 2017 at "Glia"
DOI: 10.1002/glia.23165
Abstract: A striking aspect of tissue regeneration is its uneven distribution among different animal classes, both in terms of modalities and efficiency. The retina does not escape the rule, exhibiting extraordinary self‐repair properties in anamniote species… read more here.
Keywords: glial cell; cell reactivation; ller glial; cell ... See more keywords
Müller Glial Cells Participate in Retinal Waves via Glutamate Transporters and AMPA Receptors
Sign Up to like & getrecommendations! Published in 2019 at "Cell reports"
DOI: 10.1016/j.celrep.2019.05.011
Abstract: SUMMARY Retinal waves, the spontaneous patterned neural activities propagating among developing retinal ganglion cells (RGCs), instruct the activity-dependent refinement of visuotopic maps. Although it is known that the wave is initiated successively by amacrine cells… read more here.
Keywords: glial cells; ampa receptors; glutamate transporters; ller glial ... See more keywords
Rebuilding the Retina: Prospects for Müller Glial-mediated Self-repair
Sign Up to like & getrecommendations! Published in 2019 at "Current Eye Research"
DOI: 10.1080/02713683.2019.1669665
Abstract: ABSTRACT Retinal degeneration is a leading cause of untreatable blindness in the industrialised world. It is typically irreversible and there are few curative treatments available. The use of stem cells to generate new retinal neurons… read more here.
Keywords: rebuilding retina; self repair; ller glial; retina prospects ... See more keywords
SIRT4 Is Highly Expressed in Retinal Müller Glial Cells
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Neuroscience"
DOI: 10.3389/fnins.2022.840443
Abstract: Sirtuin 4 (SIRT4) is one of seven mammalian sirtuins that possesses ADP-ribosyltransferase, lipoamidase and deacylase activities and plays indispensable role in metabolic regulation. However, the role of SIRT4 in the retina is not clearly understood.… read more here.
Keywords: sirt4; sirt4 highly; expression; ller glial ... See more keywords
Neural and Müller glial adaptation of the retina to photoreceptor degeneration
Sign Up to like & getrecommendations! Published in 2022 at "Neural Regeneration Research"
DOI: 10.4103/1673-5374.354511
Abstract: The majority of inherited retinal degenerative diseases and dry age-related macular degeneration are characterized by decay of the outer retina and photoreceptors, which leads to progressive loss of vision. The inner retina, including second- and… read more here.
Keywords: degeneration; glial adaptation; retina; ller glial ... See more keywords