LMP1 signaling pathway activates IRF4 in latent EBV infection and a positive circuit between PI3K and Src is required
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DOI: 10.1038/onc.2016.380
Abstract: Interferon (IFN) regulatory factors (IRFs) have crucial roles in immune regulation and oncogenesis. We have recently shown that IRF4 is activated through c-Src-mediated tyrosine phosphorylation in virus-transformed cells. However, the intracellular signaling pathway triggering Src… read more here.
Keywords: pi3k; lmp1 signaling; signaling pathway; activation ... See more keywords