Co-inhibition of immunoproteasome subunits LMP2 and LMP7 enables prevention of transplant arteriosclerosis.
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DOI: 10.1093/cvr/cvac181
Abstract: AIMS The loss of vascular wall cells in allotransplanted arteries is the initial event leading to transplant arteriosclerosis (TA) and ensuing loss of allograft function. Pharmacological agents able to prevent TA are currently lacking. We… read more here.
Keywords: immunoproteasome; inhibition; transplant arteriosclerosis; rejection ... See more keywords