Short LNA-modified oligonucleotide probes as efficient disruptors of DNA G-quadruplexes
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DOI: 10.1093/nar/gkac569
Abstract: Abstract G-quadruplexes (G4s) are well known non-canonical DNA secondary structures that can form in human cells. Most of the tools available to investigate G4-biology rely on small molecule ligands that stabilise these structures. However, the… read more here.
Keywords: lna modified; modified oligonucleotide; lna; short lna ... See more keywords