Identification of a TGF-β/SMAD/lnc-UTGF positive feedback loop and its role in hepatoma metastasis
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DOI: 10.1038/s41392-021-00781-3
Abstract: Aberrant activation of the TGF-β/SMAD signaling pathway is often observed in hepatocellular carcinoma (HCC). Whether lncRNA regulates the TGF-β/SMAD signaling remains largely unknown. Here, we identified an oncogenic lncRNA that was upregulated in HCC and… read more here.
Keywords: positive feedback; lnc utgf; tgf smad; metastasis ... See more keywords