Long noncoding RNA lncARSR promotes hepatic lipogenesis via Akt/SREBP-1c pathway and contributes to the pathogenesis of nonalcoholic steatohepatitis.
Sign Up to like & getrecommendations! Published in 2018 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2018.03.127
Abstract: Non-alcoholic fatty liver disease and steatohepatitis (NAFLD and NASH) account for the majority of liver disease in industrialized countries. However, the pathogenesis still unclear. Long non-coding RNAs (lncRNAs) has been reported to be involved in… read more here.
Keywords: long noncoding; lipogenesis; lncarsr; steatohepatitis ... See more keywords
Long noncoding RNA lncARSR promotes hepatic cholesterol biosynthesis via modulating Akt/SREBP‐2/HMGCR pathway
Sign Up to like & getrecommendations! Published in 2018 at "Life Sciences"
DOI: 10.1016/j.lfs.2018.04.028
Abstract: Aims: Disruption of cholesterol homeostasis has been identified as a major factor in the pathogenesis of atherosclerosis, myocardial infarction, and strokes. Long noncoding RNAs (lncRNAs) have emerged as critical players in cellular cholesterol metabolism, but… read more here.
Keywords: srebp hmgcr; long noncoding; lncarsr; cholesterol ... See more keywords