LncRNA embryonic stem cells expressed 1 (Lncenc1) is identified as a novel regulator in neuropathic pain by interacting with EZH2 and downregulating the expression of BAI1 in mouse microglia.
Sign Up to like & getrecommendations! Published in 2020 at "Experimental cell research"
DOI: 10.1016/j.yexcr.2020.112435
Abstract: LncRNA embryonic stem cells expressed 1 (Lncenc1), named after its high expression in naïve embryonic stem cells (nESCs), has been rarely studied in almost all pathological processes. Evidences suggest that Lncenc1 is likely to work… read more here.
Keywords: bai1; lncenc1; ezh2; expression ... See more keywords
Monitoring the promoter activity of long noncoding RNAs and stem cell differentiation through knock-in of sgRNA flanked by tRNA in an intron
Sign Up to like & getrecommendations! Published in 2021 at "Cell Discovery"
DOI: 10.1038/s41421-021-00272-3
Abstract: Dear Editor, The majority of mammalian genome is transcribed to RNA transcripts, of which only a very small percentage code for proteins. As a result, thousands of RNAs that do not code for proteins are… read more here.
Keywords: intron; lncenc1; expression; differentiation ... See more keywords