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   Articles with "lncrna" as a keyword



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LncRNA TUG1 Acts as a Competing Endogenous RNA to Mediate CTGF Expression by Sponging miR-133b in Myocardial Fibrosis after Myocardial Infarction.

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recommendations! Published in 2021 at "Cell biology international"

DOI: 10.1002/cbin.11707

Abstract: Myocardial fibrosis is one of the basic causes of many cardiovascular diseases. Noncoding RNAs (ncRNAs), including microRNA (miRNA) and long noncoding RNA (lncRNA), have been reported to play an indispensable role in myocardial fibrosis. The… read more here.

Keywords: mir 133b; myocardial fibrosis; expression; ctgf ... See more keywords
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LINC00449 regulates the proliferation and invasion of acute monocytic leukemia and predicts favorable prognosis

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recommendations! Published in 2020 at "Journal of Cellular Physiology"

DOI: 10.1002/jcp.29487

Abstract: Acute myeloid leukemia (AML) is a highly aggressive disease that causes high mortality. Long noncoding RNA (lncRNA) have studied in recent years that could be a potential biomarker and therapeutic target. Therefore, it is urgently… read more here.

Keywords: proliferation invasion; target; linc00449; leukemia ... See more keywords
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Isothermal detection of lncRNA using T7 RNA polymerase mediated amplification coupled with fluorescence-based sensor.

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recommendations! Published in 2021 at "Analytical biochemistry"

DOI: 10.1016/j.ab.2021.114212

Abstract: In this study, the isothermal detection of a cervical cancer-associated long non-coding RNA (lncRNA), namely, lncRNA-ATB, was performed for the first time with high selectivity and sensitivity via a T7 RNA polymerase transcription-mediated amplification system… read more here.

Keywords: detection; fluorescence; rna polymerase; amplification ... See more keywords
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PILAR1, a novel prognostic LncRNA, reveals the presence of a unique subtype of lung adenocarcinoma patients with KEAP1 mutations.

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recommendations! Published in 2019 at "Gene"

DOI: 10.1016/j.gene.2018.12.060

Abstract: Lung Adenocarcinoma (LUAD) is the most common cause of lung cancer-related deaths. Long non-coding RNAs (LncRNAs) play an essential role in cancer development and progression. In this study, we identified PILAR1, a prognostic and overexpressed… read more here.

Keywords: lung adenocarcinoma; lung; pilar1 novel; novel prognostic ... See more keywords
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WITHDRAWN: LncRNA-MALAT1 modulates pyroptosis of renal tubular cells induced by high glucose in diabetic nephropathy (DN) by via miR-206 regulation

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recommendations! Published in 2021 at "Journal of King Saud University - Science"

DOI: 10.1016/j.jksus.2021.101367

Abstract: Abstract Objective Renal failure is very common in Diabetic nephropathy (DN) at terminal stage. Long-chain non-coding RNA (LncRNA) improves DN by regulating microRNA (miR). In this study, we investigate the role of MALAT1/miR-206 on high… read more here.

Keywords: malat1; mir 206; renal tubular; lncrna ... See more keywords
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STRring up Cancer with lncRNA.

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recommendations! Published in 2018 at "Molecular cell"

DOI: 10.1016/j.molcel.2018.10.026

Abstract: In this issue of Molecular Cell, Yap et al. (2018) identify a novel lncRNA (PNCTR) that contains short tandem repeats that trap the RNA splicing factor PTBP1 in the perinucleolar compartment and link this sequestration activity… read more here.

Keywords: cancer lncrna; cancer; cell; strring cancer ... See more keywords
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LncRNA uc003fir promotes CCL5 expression and negatively affects proliferation and migration of trophoblast cells in preeclampsia.

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recommendations! Published in 2018 at "Pregnancy hypertension"

DOI: 10.1016/j.preghy.2018.08.449

Abstract: OBJECTIVE To evaluate the role of lncRNA uc003fir in the progression and development of preeclampsia (PE). DESIGN Paired test using placental tissue collected from PE women and normally pregnant women. SETTING First Hospital of Soochow… read more here.

Keywords: proliferation migration; expression; lncrna uc003fir; trophoblast cells ... See more keywords
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Non-coding deletions identify Maenli lncRNA as a limb-specific En1 regulator.

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recommendations! Published in 2021 at "Nature"

DOI: 10.1038/s41586-021-03208-9

Abstract: Long non-coding RNAs (lncRNAs) can be important components in gene-regulatory networks1, but the exact nature and extent of their involvement in human Mendelian disease is largely unknown. Here we show that genetic ablation of a… read more here.

Keywords: limb; specific en1; limb specific; non coding ... See more keywords
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Hovlinc is a recently evolved class of ribozyme found in human lncRNA

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recommendations! Published in 2021 at "Nature Chemical Biology"

DOI: 10.1038/s41589-021-00763-0

Abstract: Although naturally occurring catalytic RNA molecules—ribozymes—have attracted a great deal of research interest, very few have been identified in humans. Here, we developed a genome-wide approach to discovering self-cleaving ribozymes and identified a naturally occurring… read more here.

Keywords: hovlinc; class; ribozyme; rna ... See more keywords
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A novel biosensor for the ultrasensitive detection of the lncRNA biomarker MALAT1 in non-small cell lung cancer

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recommendations! Published in 2021 at "Scientific Reports"

DOI: 10.1038/s41598-021-83244-7

Abstract: Long non-coding RNAs (lncRNAs) have been proposed as diagnostic biomarkers for the screening of non-small cell lung cancer and monitoring disease progression. Accordingly, new, rapid, and cost-effective lncRNA biosensors that can be used clinically are… read more here.

Keywords: detection; biosensor; non small; cancer ... See more keywords
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Regulation of gene expression by the action of a fungal lncRNA on a transactivator

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recommendations! Published in 2019 at "RNA Biology"

DOI: 10.1080/15476286.2019.1663618

Abstract: ABSTRACT Long non-coding RNAs (lncRNAs) are crucial factors acting on regulatory processes in eukaryotes. Recently, for the first time in a filamentous fungus, the lncRNA HAX1 was characterized in the ascomycete Trichoderma reesei. In industry,… read more here.

Keywords: gene expression; expression action; expression; regulation gene ... See more keywords