Silencing lncRNA-DGCR5 increased trophoblast cell migration, invasion and tube formation, and inhibited cell apoptosis via targeting miR-454-3p/GADD45A axis.
Sign Up to like & getrecommendations! Published in 2021 at "Molecular and cellular biochemistry"
DOI: 10.1007/s11010-021-04161-x
Abstract: Long noncoding RNA (lncRNA)-DGCR5 has been recognized as a potential tumor progression regulator, while its expression and specific functions in preeclampsia (PE) development remain unveiled. The expressions of miR-454-3p, lncRNA-DiGeorge syndrome critical region gene 5… read more here.
Keywords: lncrna dgcr5; tube formation; mir 454;
A Wnt-induced lncRNA-DGCR5 splicing switch drives tumor-promoting inflammation in esophageal squamous cell carcinoma.
Sign Up to like & getrecommendations! Published in 2023 at "Cell reports"
DOI: 10.2139/ssrn.4287908
Abstract: Alternative splicing (AS) is a critical mechanism for the aberrant biogenesis of long non-coding RNA (lncRNA). Although the role of Wnt signaling in AS has been implicated, it remains unclear how it mediates lncRNA splicing… read more here.
Keywords: cell; lncrna dgcr5; wnt; splicing switch ... See more keywords